Publications by authors named "O Bernus"
The international Working Group of the Signal Summit is a consortium of experts in the field of cardiac electrophysiology dedicated to advancing knowledge on understanding and clinical application of signal recording and processing techniques. In 2023, the working group met in Reykjavik, Iceland, and laid the foundation for this manuscript. Atrial fibrillation (AF) is the most common arrhythmia in adults, with a rapidly increasing prevalence worldwide.
View Article and Find Full Text PDFArticle Synopsis
- Heterogeneities in ventricular repolarization play a key role in causing ventricular fibrillation (VF), but the specific triggers and their origins are not well understood.
- The study aimed to investigate how VF is initiated in a model of repolarization heterogeneity and to pinpoint where these triggers arise.
- Using isolated porcine right ventricles, researchers induced VF after creating a repolarization gradient, discovering that triggers consistently originated from the border zone between altered and normal repolarization areas.
Ithildin is an open-source library and framework for efficient parallelized simulations of excitable media, written in the C++ programming language. It uses parallelization on multiple CPU processors via the message passing interface (MPI). We demonstrate the library's versatility through a series of simulations in the context of the monodomain description of cardiac electrophysiology, including the S1S2 protocol, spiral break-up, and spiral waves in ventricular geometry.
View Article and Find Full Text PDFBackground: Idiopathic ventricular fibrillation (IVF) can be associated with undetected distinct conditions such as microstructural cardiomyopathic alterations (MiCM) or Purkinje (Purk) activities with structurally normal hearts.
Objectives: This study sought to evaluate the characteristics of recurrent VF recorded on implantable defibrillator electrograms, associated with these substrates.
Methods: This was a multicenter collaboration study.