Publications by authors named "O Berger"

Article Synopsis
  • Recent research indicates that blocking the interaction between valosin-containing protein (VCP) and mutant huntingtin (mtHtt) can help prevent mitochondrial damage in Huntington's disease models.
  • A newly developed protein-like polymer (PLP) has shown effectiveness in cellular and animal models, significantly inhibiting mitochondrial destruction and proving more stable than control oligopeptides.
  • PLP has a remarkably longer circulation half-life (152 hours) and outperforms free peptide in efficacy tests, suggesting it could be a promising platform for developing treatments for central nervous system disorders.
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Background: Giant cell tumor of bone (GCTB) is a locally aggressive tumor that may affect the bones of the hand and rarely causes pulmonary metastasis. It exhibits a variable recurrence rate after surgical interventions, which presents challenges in its management. This systematic review aims to delineate recurrence rates and identify risk factors for GCTB in the hand.

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Granular cell tumor (GCT), a rare Schwann cell-derived lesion, typically manifests as a benign skin or soft tissue growth. We report a case of GCT mimicking cellulitis on a woman's foot at first presentation. Despite initial misdiagnosis, histological examination confirmed GCT, guiding successful excision and reconstruction.

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Background: Nipple adenomas (NAs) are rare benign proliferative tumors presenting as palpable nodules, erosive lesions, or nipple discharge, mimicking other conditions. This systematic review categorizes cases into sole NA (ONA) or co-diagnoses with other conditions (CONA) to enhance clinical recognition, diagnosis, and treatment efficacy.

Methods: Following PRISMA guidelines, a PubMed search was conducted for NA.

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Background: Breast reconstruction is a standard procedure in postmastectomy plastic surgery. The necessity of routine histological examinations for mastectomy scars during delayed reconstruction remains a topic of debate. We evaluated the need for histological examination of scars during delayed breast reconstruction.

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