Publications by authors named "O Barak"
Vasopressin (AVP), a nonapeptide synthesized predominantly by magnocellular hypothalamic neurons, is conveyed to the posterior pituitary the pituitary stalk, where AVP is secreted into the circulation. Known to regulate blood pressure and water homeostasis, it also modulates diverse social behaviors, such as pair-bonding, social recognition and cognition in mammals including humans. Importantly, AVP modulates social behaviors in a gender-specific manner, perhaps, due to gender differences in the distribution in the brain of AVP and its main receptor AVPR1a.
View Article and Find Full Text PDFThe relation between neural activity and behaviorally relevant variables is at the heart of neuroscience research. When strong, this relation is termed a neural representation. There is increasing evidence, however, for partial dissociations between activity in an area and relevant external variables.
View Article and Find Full Text PDFArticle Synopsis
- High levels of follicle-stimulating hormone (FSH) in post-menopausal women are linked to the development of Alzheimer's disease (AD), as shown by studies in mice.
- Mice lacking FSH receptors displayed improved spatial memory, indicating that blocking FSH signaling can help prevent memory loss related to aging and AD-like pathology.
- The findings suggest that targeting FSH could be a potential strategy for preventing memory deficits in post-menopausal women.
Article Synopsis
- * A study analyzed data from 411 patients to assess blood-based biomarkers (NLR, PLR, FIB4, etc.) for predicting hospital mortality, using statistical techniques to gauge their impact on mortality rates.
- * Key findings revealed that NLR, PLR, and FIB4 were strong predictors of hospital mortality, while other markers like INPR, APRI, LMR, and ALBI did not significantly influence mortality predictions in this context.