Publications by authors named "O B Stepura"

The article is devoted to pharmacoeconomic aspects of treatment of arterial hypertension including its combination with diabetes mellitus. Data of four studies of comparison of clinical and economical effectiveness of treatment with original enalapril and its fixed combination with hydrochlorothiazide with some generic preparations of enalapril are presented. It has been shown that original enalapril has advantages over generics and from position of treatment cost.

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Background: Aim of this study was to evaluate adjuvant magnesium orotate on mortality and clinical symptoms in patients with severe heart failure under optimal cardiovascular medication.

Methods: In a monocentric, controlled, double-blind study, 79 patients with severe congestive heart failure (NYHA IV) under optimal medical cardiovascular treatment were randomised to receive either magnesium orotate (6000 mg for 1 month, 3000 mg for about 11 months, n = 40) or placebo (n = 39). Both groups were comparable in demographic data, duration of heart failure and pre- and concomitant treatment.

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Background: Aim of this study was to evaluate adjuvant magnesium orotate on mortality and clinical symptoms in patients with severe heart failure under optimal cardiovascular medication.

Methods: In a monocentric, controlled, double-blind study, 79 patients with severe congestive heart failure (NYHA IV) under optimal medical cardiovascular treatment were randomised to receive either magnesium orotate (6000 mg for 1 month, 3000 mg for about 11 months, n=40) or placebo (n=39). Both groups were comparable in demographic data, duration of heart failure and pre- and concomitant treatment.

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Aim: To examine lymphocyte ability to synthetize interferon-gamma in patients with mitral prolapse (MP).

Material And Methods: The diagnosis of MP was made in 75 patients at echocardiography. ECG monitoring was made and the study of the ability of blood lymphocytes to produce IFN-gamma (If-g).

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