New Complexes of Actinides with Monobromoacetate Ions: Synthesis and Structures.

Synthesis, FTIR spectral study, and X-ray diffraction analysis of single crystals of (CH)N[UO(mba)] (), (CH)N[NpO(mba)(NO)] (), (CH)N[PuO(mba)(NO)] (), and (CH)N[NpO(mba)(NO)] (), where mba is a monobromoacetate ion (CHBrCOO), were conducted. The main structural units of crystals - are mononuclear anionic complexes of the [AnO(mba)], [AnO(mba)(NO)], or [AnO(mba)(NO)] composition. All these complex units are characterized with the same crystal-chemical formula ( = AnO and = CHBrCOO or NO ).

Transdermal platform for the delivery of the antifungal drug naftifine hydrochloride based on porous vaterite particles.

Development of a skin-targeted particulate delivery system providing an extended or sustained release of the payload and a localized therapeutic effect is one of the main challenges in the treatment of fungal skin infections. In the topical administration of antifungals, the drug should penetrate into the stratum corneum and lower layers of the skin in effective concentrations. Here, we introduce biodegradable calcium carbonate carriers containing 4.

Physical properties and cytotoxicity of silver nanoparticles under different polymeric stabilizers.

At present day, silver nanoparticles are widely used in different fields of human activity. Due to the unique combination of physical and chemical properties, silver nanoparticles have high reactivity and antibacterial activity against microorganisms. For the same reason, silver nanoparticles can render a cytotoxic effect on eukaryotic cells.

Anti-Biofilm Activity of Polyazolidinammonium Modified with Iodine Hydrate Ions against Microbial Biofilms of Uropathogenic Coliform Bacteria.

The dynamics of microbial biofilm formation by standard strain and by clinical strains of uropathogenic coliform bacteria was investigated in vitro and the effect of sublethal concentrations of the polymer compound polyazolidinammonium modified with iodine hydrate ions on the initial stages of biofilm formation was assessed. Treatment of immunological plate wells with the polymeric compound prevented film formation, especially in case of clinical E. coli strain carrying FimH virulence gene.

[ANTIMICROBIAL ACTIVITY OF POLYAZOLIDINAMMONIUM, MODIFIED WITH HYDRATE-IONS OF IODINE].

Aim: Study of antimicrobial activity of a polymer compound--polyazolidinammonium, modified with hydrate-ions of iodine.

Materials And Methods: Antimicrobial activity of polyazolidinammonium, modified with hydrate-ions of iodine, against reference strains and clinical isolates of Gram positive and negative bacteria, microscopical fungi, as well as RNA viruses was studied.

Results: High antibacterial activity of the studied compound was established, especially against Gram positive bacteria.