[Noninvasive transcranial electrostimulation of endorphin structures of the brain as a reparation activator: experimental and clinical parallels].

The authors evaluated the capacities of transcranial electrostimulation and the specific features of its impact on reparative regeneration of damaged tissues of different types, such as the dermal and gastroduodenal epithelium, hepatic cells, connective tissue, peripheral nerve fibers, on animal experimental pathological models and compared with the results of treatment of respective pathology in patients.

[The effect of transcranial electrostimulation of the opioid structures of the brain on peripheral nerve regeneration in the rat].

Transcranial electrical stimulation of opioid brain structures was studied for its effect on the sciatic nerve of rat after transection and microsurgical restoration of the nerve. It was shown that electrical stimulation accelerated regeneration of sensory and motor fibres of the sciatic nerve. Participation of endogenous opioid peptides in the regeneration of peripheral nerves is discussed.

[Effects of transcranial electrostimulation of the opioid systems on reparative processes in patients with myocardial infarct].

Sixty three patients with primary excessive myocardial infarction (MI) were examined. Transcranial electric stimulation (TES) was demonstrated to contribute to more rapid formation of a postinfarction scar, development of compensatory hypertrophy of the preserved myocardium, and improvement of cardiac contractility. TES-induced activation of the endogenous opioid system was found to be one of the mechanisms responsible for stimulation of reparative processes in patients with MI.