[The possibilities of congenital pathology primary prophylaxis as responsibility of general practitioner in Ukraine].

Unlabelled: The aim was to study some tendencies of congenital pathology primary prophylaxis in context of Governmental measures and general practitioner's activity.

Materials And Methods: The information basis of investigation was made up from foreign and home publications, lawmaking documents and data of questioners. Questioners were filled in by doctors who obtained general practitioner qualification (152 persons).

[Beta-adrenoblockaders and calcium antagonists in the treatment of patients with ischemic heart disease combined with hypertension].

The authors studied 67 patients with ischemic heart disease associated with hypertensive disease and revealed that the use of beta-adrenoblockaders and calcium antagonists resulted in a reduction of the manifestations of the disease, increase of physical load tolerance, optimization of its hemodynamic and oxygen provision. In patients under 60 years of age of beta-adrenoblockaders resulted in an increase of the myocardial contractility. This was not observed in those over 60 years of age.

[Modelling of a combined immunodeficiency state by splenectomy and alloimmunization with lymph node antigens].

Autoimmune pathology was modelled in splenectomized animals by allosensitization with lymphoid tissue in association with Freund's adjuvant. It was found that splenectomy in guinea pigs produces stable disorders of homeostasis and morphological picture of the heart, liver, inguinal lymph nodes as well as a imbalance of the autoregulation mechanisms. The authors obtained an experimental model of autoimmune pathology that may be used for investigation of the pathogenesis of these states as well as for developing methods of corrective therapy.