Publications by authors named "O Arola"
Article Synopsis
- Inhaled xenon combined with hypothermia was tested on comatose patients who survived out-of-hospital cardiac arrest (OHCA) to see if it could protect gray matter in the brain.
- A study of 110 patients found that those who received inhaled xenon and temperature management showed less reduction in brain gray matter volume, especially in areas like the amygdala and temporal gyrus, compared to those who received only temperature management.
- The results suggest that inhaled xenon can help preserve brain structure in this patient group, highlighting its potential therapeutic benefits.
Article Synopsis
- This study investigates the effects of inhaled xenon on metabolic outcomes in out-of-hospital cardiac arrest survivors receiving targeted temperature management.
- Blood samples showed that increased lactate and decreased branched-chain amino acids (BCAAs) were associated with higher mortality rates at 24 and 72 hours post-arrest.
- The findings suggest that high levels of lactate and alanine, along with low BCAAs and small HDL cholesterol, are linked to negative outcomes, while inhaled xenon did not significantly impact the metabolic profile of patients.
Background: Ventricular extrasystoles (VESs) are common and often harmless in a healthy heart, but they can significantly affect the quality of life. If changes in lifestyle and antiarrhythmic medication are not enough, invasive and often curative catheter ablation can be considered. Better understanding of the conformation of VESs with a 12-lead ECG, as well as their precise localization, have increased their treatment with catheter ablation.
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- The study aimed to compare the effectiveness of brain imaging techniques (DTI, 1H-MRS), serum NSE, and motor scores in predicting poor neurological outcomes in comatose patients after out-of-hospital cardiac arrest.
- Results showed that the predictive accuracy of these methods was not significantly better than the motor score alone, although combining data from multiple methods slightly improved accuracy.
- Ultimately, while there is a small benefit in using advanced imaging together with motor scores and seizures for prediction, the complexity and cost make routine use of DTI/MRS in clinical settings unnecessary.
Introduction: Inner ear decompression sickness (IEDCS) is a condition from which only a minority of patients recover completely, the majority ending up with mild to moderate residual symptoms. IEDCS has been reported after deep technical dives using mixed breathing gases, and moderate recreational dives with compressed air as the breathing gas. Considering this and the high proportion of technical diving in Finland, a comparison between IEDCS cases resulting from technical and recreational dives is warranted.
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