Precise estimation of individual radiation dose utilizing biomaterials (fingernail, bone, and tooth) is very challenging due to their complex sample processing. Despite, tooth enamel, the most mineralized tissue of tooth is used for this purpose due to its high radiation sensitivity and ability to produce radiation induced long lived CO radicals. However, human teeth are not always available, and invasive nature of sample collection adds to the complexity making dose estimation difficult.
View Article and Find Full Text PDFSurface mount electronic devices (like resistors, capacitors, and inductors) extracted from the portable electronic devices (mobile phones, USB drives, etc.) have been studied for dose reconstruction using luminescence techniques for radiological or nuclear emergencies. In this work, carbon coated ceramic resistors removed from the electronic instruments are analyzed using thermo luminescence (TL) technique for the retrospective dose reconstruction.
View Article and Find Full Text PDFMutat Res Genet Toxicol Environ Mutagen
November 2020
Radiation has widespread applications in medicine. However, despite the benefits of medical radiation exposures, adverse long-term health effects are cause for concern. Protein and gene biomarkers are early indicators of cellular response after low-dose exposure.
View Article and Find Full Text PDFMutat Res Genet Toxicol Environ Mutagen
August 2019
Interventional radiology-based imaging is the preferred choice for diagnosis and therapy of many complex diseases, despite possible adverse effects of the radiation exposures. We have measured induced DNA damage and changes in gene expression in relation to entrance surface dose (ESD) in peripheral blood samples of patients (n = 51) who underwent neuro-interventional radiological procedures. The ESD values, measured by thermoluminescence dosimetry, were 4.
View Article and Find Full Text PDFRecent epidemiological studies in various cohorts confirm that radiation induced cataract may occur at a threshold dose as low as 0.5 Gy. ICRP has recognised the higher radiosensitivity of eye lens and recommended to reduce annual eye lens dose limit from 150 to 20 mSv.
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