Publications by authors named "O Albayrak"
Objective: In our study, the protective effect of dodder plant extract against encephalopathy induced by cholestatic liver disease model was investigated.
Methods: Spraque Dawley rats were used in the study. For the cholestatic liver disease model, the bile duct ligation (BDL) was applied.
Article Synopsis
- Single-cell RNA sequencing (scRNAseq) and flow cytometry in skin research are expensive and complex, often limiting their use for researchers, particularly when analyzing both RNA and protein from the same samples.* -
- The study introduces a new sample multiplexing strategy that allows for simultaneous scRNAseq and flow cytometry on paired blood and skin samples, enhancing data collection and analysis across healthy and inflamed specimens.* -
- This novel approach not only cuts costs by 2-4 times and reduces technical issues but also includes detailed protocols for implementation, making advanced skin analysis techniques more accessible for researchers.*
Article Synopsis
- Hymenoptera venom allergy (HVA) is a major cause of severe allergic reactions; a study analyzed 76 adults and 36 children to explore clinical features and immunologic changes after venom immunotherapy (VIT).
- Cardiovascular symptoms were more common in adults, while children primarily experienced skin reactions; risk factors for severe reactions included lower urticaria rates and higher serum tryptase levels in adults.
- VIT significantly increased specific immunoglobulin G4 (sIgG4) levels in patients, with notable increases seen in Apis and Vespula groups, showing different allergic responses between adults and children after one year of treatment.
Electron beam lithography (EBL) stands out as a powerful direct-write tool offering nanometer-scale patterning capability and is especially useful in low-volume R&D prototyping when coupled with pattern transfer approaches like etching or lift-off. Among pattern transfer approaches, lift-off is preferred particularly in research settings, as it is cost-effective and safe and does not require tailored wet/dry etch chemistries, fume hoods, and/or complex dry etch tools; all-in-all offering convenient, 'undercut-free' pattern transfer rendering it useful, especially for metallic layers and unique alloys with unknown etchant compatibility or low etch selectivity. Despite the widespread use of the lift-off technique and optical/EBL for micron to even sub-micron scales, existing reports in the literature on nanofabrication of metallic structures with critical dimension in the 10-20 nm regime with lift-off-based EBL patterning are either scattered, incomplete, or vary significantly in terms of experimental conditions, which calls for systematic process optimization.
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- Radiofrequency ablation is a treatment for knee osteoarthritis, and this study aimed to compare the effectiveness of treating 2 nerve branches versus 3.
- The study involved 41 patients who were divided into two groups, one receiving treatment on 2 branches and the other on 3 branches, with pain and quality of life assessed before and after the procedure.
- Results showed notable improvements in pain and physical function for both groups, but no significant difference in effectiveness between the 2-branch and 3-branch treatments.