Collagen type I is the main structural unit in skin tissue and is therefore used preferentially in skin tissue scaffolds. However, collagen-based 3D scaffolds have weak aqueous stability and degradation profiles in their uncross-linked states and chemical cross-linking reagents arise toxicity concerns, which generally restrict the spectrum of their biomedical applicability. Here, the research goal is to photochemically cross-link collagen type I with rose bengal (RB) when subjected to green laser light and to investigate the effect of silk sericin-capped gold nanoparticles (S-AuNP) when incorporated into scaffolds on the cross-linking process and thus on the scaffold properties.
View Article and Find Full Text PDFTransition metal dichalcogenides (TMDs) receive significant attention due to their outstanding electronic and optical properties. In this study, we investigate the electronic, optical, and thermoelectric properties of single and few layer [Formula: see text] in detail utilizing first-principles methods based on the density functional theory (DFT). Within the scope of both PBE and HSE06 including spin orbit coupling (SOC), the simulations predict the electronic band gap values to decrease as the number of layers increases.
View Article and Find Full Text PDFBackground: Hartmann's Procedure (HP) is performed for cancer, trauma or benign diseases of the left colon. It is regarded as a solution to avoid a risky anastomosis with the intent to reverse after the diseased colon is given time to recover. This reversal has been associated with a potential morbidity and mortality.
View Article and Find Full Text PDFBackground: Red cell distribution width (RDW) has been shown to have predictive properties in different diseases as well as solid cancers.
Aim: We aimed to investigate the discriminative properties of RDW in benign and malignant breast lesions.
Subjects And Methods: In a retrospective cohort study the files of patients who underwent surgery for fibroadenomas (Group A) and breast cancer with axillary lymph node metastasis (Group B) were reviewed.
Int J Biol Macromol
January 2022
Here, gold nanoparticles (AuNPs) were synthesized upon exposure to nano-pulsed Nd-YAG laser irradiation in de-ionized water (PLAL) and functionalized with levan polysaccharide for assessing the anticancer efficacy of doxorubicin (DOX)-conjugated levan-capped AuNPs complexes to MCF-7 breast cancer cells. According to the physicochemical test results, the increments in levan amount enhanced the colloidal stability and the drug encapsulation efficiency (DEE) significantly. For the 10L-AuNP group having the highest levan amount (10 mg/mL levan), DEE was calculated as 92.
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