Publications by authors named "O Afe Taiwo"
Epigenetic Regulation by Histone Methylation and Demethylation in Freeze-Tolerant Frog Kidney.
Cell Biochem Funct
December 2024
The wood frog (Rana sylvatica) endures whole-body freezing over the winter, with extensive extracellular ice formation and halted physiological activities. Epigenetic mechanisms, including reversible histone lysine methylation, enable quick alterations in gene expression, helping to maintain viability during freeze-thaw cycles. The present study evaluated eight histone lysine methyltransferases (KMTs), 10 histone lysine demethylases (KDMs), and 11 histone marks in wood frog kidneys.
View Article and Find Full Text PDFBackground: Studies among workers with a wide range of exposure to perfluoroalkyl substances inform risk assessments. Perfluorooctane sulfonate (PFOS), a ubiquitous environmental contaminant, was recently examined in relation to mortality and cancer incidence in an occupationally exposed population by Alexander et al. in 2024.
View Article and Find Full Text PDFArticle Synopsis
- Cadmium (Cd) causes oxidative stress in organisms, while the ethnomedicinal plant Tetrapleura tetraptera (Tt) is known for its high antioxidant properties and potential to treat various diseases.
- The study involved feeding Drosophila melanogaster different diets, including Tt extracts and cadmium chloride (CdCl), then measuring the impact on oxidative stress markers and fly health after a week.
- Results showed that T. tetraptera reduced oxidative stress caused by cadmium, improving antioxidant activity, enhancing levels of important compounds, and increasing the rate of offspring emergence, suggesting its potential as a treatment for oxidative stress-related issues.
Background: After the first Avian Influenza H5N1 outbreak in Nigerian poultry in 2006, subsequent waves of outbreaks occurred, causing substantial losses. Despite effective control measures by 2008, a resurgence in 2015 led to further losses and required depopulation efforts.
Aim: The aim of this study was to do pathology and molecular detection of influenza A subtype H9N2 virus in commercial poultry in Nigeria during 2024.
Background: The safety potential of the methanol extract of (TOM) leaf was evaluated in albino Wistar rats using biochemical, haematological, and histological indices in both acute and sub-chronic toxicity studies.
Methods: The animals were managed following the National Institute of Health (NIH) stipulated protocols for handling laboratory animals. The weight of each animal was recorded upon arrival and monitored throughout the study.