Publications by authors named "O Acha"

We retrospectively analyzed the findings of a prospective cohort of 75 children referred for thyroid nodules between 2008 and 2013. Prevalence of papillary differentiated thyroid carcinoma was 18.7%.

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Background And Aims: Hypocalcemia after thyroidectomy is caused by parathyroid trauma. There are no studies regarding the usefulness of intact parathyroid hormone (PTH) as a monitor of postoperative hypoparathyroidism tool in pediatrics. We evaluated the diagnostic accuracy of intra- and postoperative PTH to predict the risk of developing post thyroidectomy hypocalcemia in children.

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Article Synopsis
  • The study analyzed 45 pediatric patients diagnosed with differentiated thyroid carcinoma (DTC) over a 20-year period, revealing a predominance of papillary type and common presentation as solitary nodules or in conjunction with cervical adenopathy.
  • Most patients underwent complete thyroid removal and treatment with radioactive iodine, with a follow-up showing a 75% disease-free survival rate over 5 years, despite 11% experiencing recurrences.
  • The findings indicated an aggressive nature of pediatric DTC at diagnosis, with higher preoperative TSH levels linked to more advanced disease, highlighting the need for further research on associated conditions like chronic lymphocytic thyroiditis (CLT).
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Spontaneous calcific embolism is an uncommon cause of stroke. In most cases calcified cardiac valves are the sources of the emboli although embolization of calcific material from the brachiocephalic trunk has also been described. We report a case of stroke attributable to spontaneous calcific emboli from the aortic arch in which migration of the emboli was observed along the middle cerebral artery following iv tPA.

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Objective: To assess the prevalence of negative clinical outcomes associated with medication as a cause of hospital admission and to determine their characteristics (types, categories, avoidability, severity and the drug groups involved.) To determine possible risk factors related to the appearance of this problem.

Method: An observational study carried out over a three month period in a department of the university hospital, 163 patients were selected at random.

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