Generation of iPSC line from a Joubert syndrome patient with compound heterozygous mutations in CPLANE1 gene.

We generated iPSC line using skin fibroblasts obtained from a female patient affected by Joubert syndrome, caused by two compound heterozygous variants (c.143G > A; p.Gly48Glu and c.

PERCEPTION AND WILLINGNESS TO THE UPTAKE OF COVID-19 VACCINE AMONG HOUSEHOLD-HEADS IN A RURAL COMMUNITY OF SOUTH-WESTERN NIGERIA.

Background: The COVID-19 pandemic and its vaccine have been met with varying perceptions that may have both negative and positive effects on the willingness to uptake the COVID-19 vaccine. The study is set to determine the perception and willingness of the household heads to the uptake of COVID-19 vaccine in a rural community in Southwestern, Nigeria.

Materials And Methods: A cross-sectional study was carried out among 409 household heads selected through a multistage sampling technique.

Microbiological findings and prescribing trends in SARS- CoV-2 positive patients in two United Kingdom Hospitals.

Objective: To describe antibiotic prescribing and microbiological findings in patients admitted to two London hospitals with COVID-19.

Methods: This is a retrospective review of confirmed SARS-CoV-2 infected adults admitted between 9th February and 10th May 2020. Demographics, critical care unit (CCU) admission, antibiotic prescribing and microbiology results within 10 days of COVID-19 diagnosis were analysed.

Evaluation of water pollution monitoring for heavy metal contamination: A case study of Agodi Reservoir, Oyo State, Nigeria.

Heavy metals affect the suitability of aquatic environment for all purposes; hence, this study evaluated heavy metal contamination in Agodi Reservoir Oyo State, Nigeria. Atomic Absorption Spectrophotometry was used to determine heavy metal concentrations. Heavy Metal Pollution Index (HPI), Water Quality Index (WQI), Pollution Index (PI), Comprehensive Pollution Index (CPI), Contamination Index (CI), Single-Factor Pollution Index (SFPI), Heavy metal Evaluation Index (HEI), and Human Health Risk Assessments (HRA) were used to determine the extent of heavy metal pollution and their impact on the aquatic environment.