Publications by authors named "O A Toledo"

The Artisse intrasaccular device (Medtronic) offers a novel treatment option for unruptured and ruptured wide-neck bifurcating intracranial aneurysms.1 2The Artisse device features enhancements including a distal tip for dome protection, platinum band markers for improved visibility, and a bilayer high-density platinum core nitinol mesh basket for enhanced flexibility and visibility when compared with previous devices.2-7 Data from case series demonstrate the procedural safety and efficacy of the Artisse device.

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Background And Objectives: The Woven EndoBridge (WEB) device is a breakthrough in brain aneurysm treatment, widely used for intracranial wide neck and complex aneurysms, especially at bifurcations. Although effective, aneurysm recurrence can occur post-treatment and the impact of clipping angle on the WEB mesh remains unclear. In this study, using a human placenta-based ex-vivo aneurysm model, we simulated the application of aneurysm clipping on WEB-treated aneurysms to elucidate the technical aspects and nuances, particularly the influence of the angle of clip application on WEB collapse.

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  • Heavily calcified carotid stenosis (HCCS) has traditionally been challenging to treat with carotid angioplasty and stenting (CAS), but this study explores the use of the Shockwave S intravascular lithotripsy (IVL) system as a potential solution.
  • A retrospective analysis of 17 procedures combining IVL and CAS on patients with HCCS showed technical success in all cases and significant reductions in stenosis levels post-procedure.
  • The results indicated that the combined approach is safe, with a low major adverse event (MAE) rate and a promising outcome in managing both symptomatic and asymptomatic patients with HCCS.
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  • Steal syndrome occurs when blood flow is redirected through collateral vessels due to an obstruction in an artery, which can lead to conditions like subclavian steal syndrome and double steal phenomenon.
  • A case study presented involves an elderly patient suffering from cerebrovascular issues who experienced neurological symptoms while chewing, linked to specific artery blockages discovered via angiography.
  • Successful treatment was achieved by performing endovascular revascularization on the affected arteries using a specialized stent, which resolved the patient’s symptoms.
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  • The study examines the stability of the Pipeline Embolization Device (PED) in treating brain aneurysms, focusing on early generations and potential braid deformations.
  • Data was gathered from the PREMIER trial, reviewing 133 out of 141 aneurysms for issues like braid bumping and foreshortening, assessing both safety and effectiveness.
  • The results show that while a small percentage experienced braid deformations, they didn't significantly impact the device's safety or effectiveness over the follow-up period.
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