[Combination chemotherapy in the adjuvant treatment of disseminated breast cancer].

The results of clinical studies are presented on the combined chemotherapy in spread breast cancer, conducted according to the following three schedules: 1. thiophosphamide, carminomycin, vincristine, ftorafur, prednisolone, 2. diiodobenzoTEPA, carminomycin, vincristine, ftorafur, prednisolone, 3.

[Preoperative polychemotherapy in the overall treatment of locally spread breast cancer (immediate results)].

Eighty three patients with locally spread cancer of the mammary gland (stage IIIb and IIIc) were subjected to the preoperative polychemotherapy with 5-fluoruracil, methotrexate, cyclophosphane, vincristine against the background of the hormonal therapy (ovarioectomy + corticosteroids). Diminishing of the tumor bulk by 50% was noted in 53 patients. In 26 cases the effect was less pronounced, no effect was observed in 4.