Pattern-induced anchoring transitions in nematic liquid crystals.

In this paper we revisit the problem of a nematic liquid crystal in contact with patterned substrates. The substrate is modelled as a periodic array of parallel infinite grooves of well-defined cross-section sculpted on a chemically homogeneous substrate which favours local homeotropic anchoring of the nematic. We consider three cases: a sawtooth, a crenellated and a sinusoidal substrate.

Tracheal and bronchial polymeric immunoglobulin secretory immune system (PISIS) development in a porcine model.

Polymeric immunoglobulins (pIgs) mucosal secretion is mediated by the pIg secretory immune system (PISIS), which is composed of J-chain (JC) and antibody (IgM/IgA) producing cells (JC-AbPC), pIg receptor (pIgR) epithelial cell expression and the efficient release of secretory Igs (SIgs) to the mucosal lumen. A poor development or disturbances in this system may cause higher infection susceptibility, as observed in young and elderly people. In spite of this system's importance, few detailed studies regarding its development have been described in the lower respiratory tract of humans.

Effect of age and maternal antibodies on the systemic and mucosal immune response after neonatal immunization in a porcine model.

Newborn mammals are highly susceptible to respiratory infections. Although maternal antibodies (MatAb) offer them some protection, they may also interfere with their systemic immune response to vaccination. However, the impact of MatAb on the neonatal mucosal immune response remains incompletely described.

Generalized Berreman's model of the elastic surface free energy of a nematic liquid crystal on a sawtoothed substrate.

In this paper we present a generalization of Berreman's model for the elastic contribution to the surface free-energy density of a nematic liquid crystal in presence of a sawtooth substrate which favors homeotropic anchoring as a function of the wave number of the surface structure q, the tilt angle α, and the surface anchoring strength w. In addition to the previously reported nonanalytic contribution proportional to -q ln q, due to the nucleation of disclination lines at the wedge bottoms and apexes of the substrate, the next-to-leading contribution is proportional to q for a given substrate roughness, in agreement with Berreman's predictions. We characterize this term, finding that it has two contributions: the deviations of the nematic director field with respect to a reference field corresponding to the isolated disclination lines and their associated core free energies.