Publications by authors named "O A Pozdniakova"

Background: Complete following existing guidelines for management of acute coronary syndrome (ACS) is known to be associated with better outcomes. Partly this is explained by lesser adherence to recommendations in high risk patients. Aim of our study was to assess relationship between degree of following current guidelines and in hospital outcomes independently from initial assessment of risk.

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In this work we have summarized 3-years experience of the treatment of acute coronary syndrome with the use of endovascular methods and presented organizational basis allowing to realize 24-hour work of the endovascular service, and algorithm of examination and treatment of patients admitted with diagnosis of acute coronary syndrome. During the analyzed period invasive interventions were carried out in 1417 patients (transluminal angioplasty - in 93, angioplasty with stenting - in 1356 patients) with mean door to balloon time 37.7 min.

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We revealed ontogenetic features in apoptosis level, apoptosis signal proteins expression, antioxidant (alpha-tocoferoli acetate) effects in neurons of magnocellular hypothalamic centers of BALB-c mice. It was obtained that water deprivation stress leads to apoptosis initiation of neurons in both age groups. Stress-protected action of alpha-tocoferoli acetate was more significantly in young mice compared to old ones.

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