A genome-wide cytotoxicity screen of cluster F1 mycobacteriophage Girr reveals novel inhibitors of Mycobacterium smegmatis growth.

Over the past decade, thousands of bacteriophage genomes have been sequenced and annotated. A striking observation from this work is that known structural features and functions cannot be assigned for >65% of the encoded proteins. One approach to begin experimentally elucidating the function of these uncharacterized gene products is genome-wide screening to identify phage genes that confer phenotypes of interest like inhibition of host growth.

Bioremediation of industrially contaminated soil using compost and plant technology.

Compost technology can be utilized for bioremediation of contaminated soil using the active microorganisms present in the matrix of contaminants. This study examined bioremediation of industrially polluted soil using the compost and plant technology. Soil samples were collected at the vicinity of three industrial locations in Ogun State and a goldmine site in Iperindo, Osun State in March, 2014.

Antipsychotics for the management of psychosis in Parkinson's disease: systematic review and meta-analysis.

Background: Antipsychotics can exacerbate motor symptoms in Parkinson's disease psychosis.

Aims: To systematically review the literature on the efficacy and acceptability of antipsychotics for Parkinson's disease psychosis.

Method: Randomised controlled trials comparing an antipsychotic with placebo were systematically reviewed.

Advance care planning and palliative medicine in advanced dementia: a literature review.

Aims and method To assess the factors that affect the clinical use of advanced care planning and palliative care interventions in patients with dementia. A literature search of Medline, Embase and PsycINFO was performed to identify themes in advanced care planning and palliative care in dementia. Results In total, 64 articles were found, including 12 reviews, and three key areas emerged: barriers to advanced care planning, raising awareness and fostering communication between professionals and patients, and disease-specific interventions.