Publications by authors named "O A Ogundeji"
Background: A consequence of improved survival of people living with human immunodeficiency virus (HIV) (PLHIV) is an aging population with an increased risk of developing atherosclerotic cardiovascular diseases (ASCVDs). International guidelines recommend primary preventive strategies which should be integrated into routine care of PLHIV.
Aims: This study audited the ASCVD preventive practices offered to PLHIV at the adult antiretroviral clinic in Ibadan.
Background And Objective: A major modifiable risk factor for atherosclerotic cardiovascular disease is abnormalities in lipid and lipoprotein metabolism which are frequently seen in HIV as well as its treatment. Apo-E is a protein that is important in plasma lipid homeostasis and its genetic alleles have been shown to contribute to lipid abnormalities. We examined for the effect of Apo-E gene polymorphisms on plasma lipid levels in PLHIV on protease inhibitor therapy.
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- Neurotrauma is a major health issue in Nigeria, leading to high rates of illness and death, prompting a systematic review to provide valuable nationwide data.
- The study analyzed data from 45,763 patients across 254 articles, revealing a predominance of traumatic brain injuries primarily caused by road traffic accidents, with most patients being young males.
- Despite 63.7% of traumatic brain injury patients showing favorable outcomes, only 20.9% of those with spinal injuries fared similarly, highlighting the critical need for focused interventions in managing neurotrauma in the country.
Article Synopsis
- The study reviews the development and challenges of vascular neurosurgery in Nigeria by analyzing literature from 1962 to 2021.
- A total of 56 articles were evaluated, involving 3203 patients, with a moderate to high risk of bias, indicating that most studies were retrospective cohort studies and case reports.
- The findings showed that cerebrovascular accidents predominated, particularly due to trauma, with favorable outcomes reported in 48% of cases and a mortality rate of 6%, highlighting key issues in neurovascular health in Nigeria.
Objective: Spinal pathologies are prevalent in Nigeria, though epidemiological data remains sparse. This systematic review used pooled patient-level data from across the country to generate a standardized epidemiological reference.
Methods: Four research databases and gray literature sources were searched.