Vitellaria paradoxa inhibits arsenic-induced toxicity in Drosophila melanogaster via the augmentation of antioxidant system.

The Ethyl Acetate Fraction (EACF) of Ethanol Leaf Extract of Vitellaria paradoxa (ELVp) was assessed against Sodium Arsenite (SA)-induced toxicity in Drosophila melanogaster. The Gas Chromatography-Mass Spectrometry (GC-MS) analysis of EACF was carried out. The molecular docking of the compounds obtained from GC-MS was performed against D.

Epirubicin toxicity in rat's ovary and uterus: A protective role of 3-Indolepropionic acid supplementation.

The "anthracycline, Epirubicin (EPI)," in managing breast cancer, is highly cytotoxic. Tryptophan-derived 3-indolepropionic acid (3-IPA) decreases oxidative damage, and its prospect of alleviating EPI-induced cytotoxicity was examined in rats' hypothalamus-ovary-uterus axis. Female rats: Control, EPI (2.

Leaf paste of favourably modulates deleterious effects associated with exposure to diethylnitrosamine in male Wistar rats.

Objectives: Diethylnitrosamine (DEN) is found in workplaces, processed meats, tobacco smoke, whiskey, etc. It is capable of forming DNA-adducts. Fluted pumpkin ( []) is a medicinal plant, and its herbal preparations have been employed variously in ethnomedicine.

Carcinogen sodium arsenite disrupts antioxidant and redox homeostasis in .

Objectives: The inadvertent exposure to environmental contaminants has been reported to induce cancer in different animal models. Here, we investigated the toxicity of Sodium Arsenite (SA), a Class I Carcinogen in .

Methods: Harwich fly strain (1-3 days old) of both sexes were orally exposed to SA (0, 0.

Reno-Hepatoprotective and Antidiabetic Properties of Methanol Leaf Extract of in Wistar Rats.

Toxicities due to exposure to arsenic-contaminated water and the occurrence of diabetes mellitus are major health concerns. Treatment of these concerns using therapeutic measures have recorded limited success. Traditionally, (LA) has been used in managing various diseases.