Structure and innervation of paraventricular and supraoptic hypothalamic nuclei, thyroid gland, adrenals and ovaries were studied by methods of histochemistry and electron microscopy in guinea pigs following chronic treatment with lead acetate in doses 50.10 and 0.1 mg/kg per day.
View Article and Find Full Text PDFState and structural organization of the guinea pig thyroid gland were studied histochemically in distanced terms (6 months) after the single external x-ray radiation 12.9 C/kg in doze. with the following intraperitoneal introduction of 131 6.
View Article and Find Full Text PDFDaily doses of 50 mg/kg of lead acetate injected into the laboratory animals induce morphologic changes in the parenchyma of ovaries, thyroid gland, adrenals and compromises neural mediating processes in paraventricular and supraoptic nuclei of hypothalamus. The observed morphologic changes are similar to those characteristic for intensive functioning. Prolonged exposure to lead acetate (daily dose 10 mg/kg) results in adaptation and compensation, which preserves the functional potential of the organs.
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