Expression of toll-like and adhesive receptors on epithelial cells of the oral mucosa in periodontitis.

The expression of toll-like and adhesive receptors on epithelial cells of the oral mucosa changes in different pathological conditions, both local and systemic levels, in particular, in chronic periodontitis. The long-term presence of periodontal pathogenic microorganisms in the gingival furrow stimulates and supports the inflammatory process. The interaction of periodontal pathogens with epithelial cells of the oral mucosa is the first stage of the development of periodontitis.

[Effect of ribosomal proteins of respiratory bacteria on adhesive properties of buccal epitheliocytes].

Aim: Study the effect of ribosomal proteins of respiratory bacteria composing the basis of the immune-modulating preparation ribomunil on adhesive properties of buccal epithelium of healthy donors, and carry out comparison of this parameter during use of other bacterial products.

Materials And Methods: Various amounts of bacterial ribosomal proteins, Escherichia coli (serotype O127:B8) and one-day Staphylococcus aureus (strain 5983) culture supernatant were added to "buccal epitheliocytes--candida" system and incubated. Buccal cells were washed after the incubation from non-bound candida and differentiated microscopically by the amount of cells with various levels of candida adhesion.