Publications by authors named "O A Krasnova"
Article Synopsis
- Human pluripotent stem cells (hPSCs) can differentiate into any adult tissue, making them important for regenerative medicine and research into factors affecting their growth and characteristics.
- The study analyzed the migration patterns of three hPSC cell lines (AD3, CaSR, and H9) through bright-field imaging, focusing on their "good" and "bad" morphological phenotypes.
- Results showed that migration speed varied based on the cell line and growth environment, with notable differences in migration behavior between "good" and "bad" colonies, particularly in specific culture conditions.
Article Synopsis
- - The study focuses on correcting mutations in the CASR gene, which is crucial for regulating calcium levels in the body, specifically targeting mutations linked to a severe condition called neonatal primary hyperparathyroidism.
- - Researchers generated a CRISPR/Cas9 edited human induced pluripotent stem cell (hiPSC) line that successfully restored one of the mutations while preserving another, showing normal characteristics such as cell structure and growth potential.
- - The newly created hiPSC line will be used as a valuable resource for understanding calcium regulation disorders and exploring personalized medicine approaches to treat these conditions in the future.
Objective: Aim: To study the clinical anatomy of the pulmonary ligaments of young people.
Patients And Methods: Materials and Methods: The study was carried out when performing 28 autopsies of young people aged 25 to 44 years. Methods of dissection of chest organocomplexes, macro-microscopy, morphometry and planimetry, and statistical processing were used.
Mesenchymal stem cells lose the senescent phenotype under 3D cultivation.
Stem Cell Res Ther
December 2023
Background: Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment, which is essential for obtaining more relevant results. The application of 3D cell culture techniques in regenerative medicine, particularly in mesenchymal stem cell (MSC)-based research, has been extensively studied.
View Article and Find Full Text PDFTurpentine oil, owing to the presence of 7-50 terpenes, has analgesic, anti-inflammatory, immunomodulatory, antibacterial, anticoagulant, antioxidant, and antitumor properties, which are important for medical emulsion preparation. The addition of turpentine oil to squalene emulsions can increase their effectiveness, thereby reducing the concentration of expensive and possibly deficient squalene, and increasing its stability and shelf life. In this study, squalene emulsions were obtained by adding various concentrations of turpentine oil via high-pressure homogenization, and the safety and effectiveness of the obtained emulsions were studied in vitro and in vivo.
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