Publications by authors named "O A Kazyuchits"
J Photochem Photobiol B
June 2018
Article Synopsis
- Laser radiation in the blue spectral region (405 and 445 nm) inhibits the growth of Staphylococcus aureus, E. coli, and Candida albicans without needing added photosensitizers.
- Flavin compounds and endogenous metal-free porphyrins are identified as key contributors to the antimicrobial effect by sensitizing the formation of reactive oxygen species when exposed to blue light.
- Fluorescence intensity of porphyrins decreases significantly when moving from 405 nm to 445 nm, while their antimicrobial effectiveness decreases only slightly, indicating a complex interplay between different photosensitizers based on microbial cell type.
