Anti-angiogenic and anti-oxidant effects of 2-NTI indole derivative vs. suramin in ex vivo, in vivo, and in vitro studies.

Angiogenesis is an intricate pathway that involves the formation of new blood capillaries from old, functioning ones. Improper angiogenesis is a feature of numerous maladies, including malignancy and autoimmune disorders. Indole-related derivatives are believed to interfere with the mitotic spindle, inhibiting the multiplication, and invasion of cancerous human cells.

White adipose tissues and skeletal muscles as a target of chrysin during the treatment of obesity in rats.

Obesity is a rapidly growing epidemic that continues to be a major severe health problem due to its association with various adverse health consequences. Since 1975, the WHO estimates that the prevalence of obesity has tripled globally. Chrysin is a flavone that is mostly found in the Passiflore species of plants and in propolis.

Validation of harmonized cognitive assessment protocol within the Egyptian context.

This study addresses the urgent need for culturally sensitive cognitive assessments in Egypt by validating an adapted version of Harmonized Cognitive Assessment Protocol (HCAP) to the Egyptian context. This version is to be used as a part of the Egyptian Aging Survey (AL-SEHA). We enrolled 300 participants aged 55 + from diverse backgrounds and meticulously adapted the HCAP for Egypt's linguistic and cultural context.

Understanding the Food and Nutrition Insecurity Drivers in Some Emergency-Affected Countries in the Eastern Mediterranean Region from 2020 to 2024.

This research seeks to enhance the understanding of the multifaceted drivers of food and nutrition insecurity in emergency-affected countries within the Eastern Mediterranean region and investigate the dynamics of food and nutrition security in countries facing emerging emergencies. This is a descriptive aim to determine the key factors and challenges affecting food security and nutrition status in ten countries in the Eastern Mediterranean region (Afghanistan, Djibouti, Iraq, Lebanon, Pakistan, Palestine (Gaza Strip), Somalia, Sudan, Syria, and Yemen). The research reveals that all selected countries experienced severe levels of food insecurity, with many reaching Phase 3 or above according to the IPC classification.

Lightweight and Low-Parametric Network for Hardware Inference of Obstructive Sleep Apnea.

: Obstructive sleep apnea is a sleep disorder that is linked to many health complications and can even be lethal in its severe form. Overnight polysomnography is the gold standard for diagnosing apnea, which is expensive, time-consuming, and requires manual analysis by a sleep expert. Artificial intelligence (AI)-embedded wearable device as a portable and less intrusive monitoring system is a highly desired alternative to polysomnography.