Comparative analysis of the dispersion quality of oxymetazoline nasal sprays.

Metered-dose nasal sprays (MDNS) are the most widely used for treating rhinitis. Medicinal preparations in the pharmaceutical market vary in their characteristics. To identify the most effective drug, it is necessary to compare the preparations regarding various parameters.

[Comparative analysis of Kameton spraying parameters of different manufacturers].

Purpose: Based on a comparative analysis of the key dispersion parametries of spray-aerosol forms of drugs Kameton from different manufacturers the most effective drug in terms of delivery to the mucous membrane of the throat was choosen.

Material And Methods: The objects of study were 5 drugs brand Kameton, produced in the form of a metered-dose spray manufacturers of 'Firm 'VIPSMED' (RF), 'Altayvitaminy' (RF), 'Samaramedprom' (RF), 'ESCO-Pharm' (Armenia) and metered-dose aerosol - of 'Pharmstandard' (RF). Measurement of the dynamic characteristics of the spray and the dispersed composition of the spray was carried out by the method of shadow photography with digital image processing using the 'POLIS' system.