Publications by authors named "O A Ciurea"
Background And Objectives: The importance of hematological parameters has started to be explored with increased interest in many fields lately, with different studies finding an association between those parameters and inflammatory status, atherosclerosis, comorbidities, malnutrition, neoplasia and even a faster progression of chronic kidney disease (CKD). On the other hand, CKD itself presents as an inflammatory condition, in which a lot of pathways are modified and the response to an infectious agent could be less than expected. Regarding the latter aspect, in this study we aim to explore the differences between the hematologic response during a lower versus upper urinary tract infection in patients with CKD.
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- A study in Romania reviewed 1,254 adults with biopsy-proven glomerulopathies (GP) from 2008 to 2017 to assess changes in frequency and causes for kidney biopsies (KB).
- The research found that while nephrotic syndrome was a common reason for KB, its occurrence decreased significantly over the decade, with older patients showing more advanced kidney damage and chronic kidney function decline.
- Additionally, there was a notable increase in cases of diabetic nephropathy and crescentic glomerulonephritis, suggesting changes in diagnostic practices rather than an actual rise in GP prevalence among older adults.
VITAMIN D DEFICIENCY, BONE TURNOVER MARKERS AND ARTERIAL CALCIFICATIONS IN NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS.
Acta Endocrinol (Buchar)
October 2024
Introduction: Vitamin D [25(OH)D] deficiency is prevalent in chronic kidney disease (CKD), related to bone turnover and potentially involved in arterial calcifications.
Objective: To evaluate vitamin D status in non-dialysis CKD patients and its relationships with bone turnover markers (BTM) and arterial calcifications.
Design: Cross-sectional, prospective, multicentric study.
Article Synopsis
- * A study of 334 patients with IgAN and MN found that end-stage kidney disease (ESKD) was more common in the IgAN group, with lower neutrophil-to-lymphocyte ratio (NLR) and higher lymphocyte-to-C-reactive protein ratio (LCRP) being significant risk factors for ESKD in IgAN.
- * Mortality rates were similar for both groups, but lower platelet-to-lymphocyte ratio (PL
Glomerular diseases (GDs), significant causes of end-stage kidney disease, are better understood through epidemiological studies based on kidney biopsies (KBs), which provide important insights into their prevalence and characteristics. This study aims to analyze the clinicopathological features of GDs diagnosed from 2008 to 2017 at Romania's largest reference center. In this decade-long study, 1254 adult patients diagnosed with GDs were included.
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