Publications by authors named "O A Awodu"
Article Synopsis
- * The International Society on Thrombosis and Haemostasis developed a comprehensive clinical practice guideline to assist patients, caregivers, and healthcare professionals in making informed treatment decisions for congenital hemophilia A and B.
- * A diverse panel of experts prioritized 13 key clinical questions regarding treatment strategies, utilizing the GRADE approach for systematic evidence review, and sought public feedback on their recommendations.
Article Synopsis
- The study investigates the prevalence of Rh and Kell blood group antigens in Nigeria, highlighting their importance due to their immunogenic potential and impact on red blood cell transfusions.
- The research involved 302 healthy individuals from various ethnic groups, revealing high prevalence rates for most Rh antigens, while the K antigen was found to have a prevalence of 0%.
- The findings emphasize the lack of ethnic variation in antigen prevalence and suggest a need for better blood typing and matching protocols to enhance transfusion safety and minimize alloimmunization risks.
Background: The clinical prospects of hydroxyurea therapy in the management of sickle cell disease (SCD) require evaluation in the Nigerian setting to develop indigenous guidelines. This survey examines the pattern of hydroxyurea therapy, its clinico-haematologic benefits and safety profile in Nigerian SCD subjects.
Methods: A cross sectional pilot survey was carried out among 60 adult SCD subjects over 3 months.
Background: Sickle cell anemia (SCA) is an inherited hemoglobin disorder characterized by chronic anemia and occasional crises. Clinical features are variable. While some individuals are relatively stable and rarely require blood transfusion, others often require blood transfusion.
View Article and Find Full Text PDFBackground: Lupus anticoagulant (LA) is a heterogeneous group of antibodies that causes a variety of clinical and laboratory effects; has been described in infections such as human immunodeficiency virus. LA has not been previously described in Nigerians with human immunodeficiency virus infection on highly active antiretroviral therapy (HAART).
Aim: To determine the frequency of LA in patients infected with the human immunodeficiency virus on HAART.