Publications by authors named "Oʼmalley A"

Despite the extensive use of network autocorrelation models in social network analysis, network autocorrelation models for binary dependent variables have received surprisingly scant attention. In this paper, we develop four network autocorrelation models for a binary random variable defined by whether the peer effect (also termed social influence or contagion) acts on latent continuous outcomes leading to an indirect effect under a normal or a logistic distribution or on the probability of the observed outcome itself under a probit or a logit link function defining a direct effect to account for interdependence between outcomes. For all models, we use a Bayesian approach for model estimation under a uniform prior on a transformed peer effect parameter ( ) designed to enhance model computation and compare results to those under the uniform prior for .

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Unlabelled: When an hypothesized peer effect (also termed social influence or contagion) is believed to act between units (e.g., hospitals) above the level at which data is observed (e.

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Background: Oncology outreach is a common strategy for addressing cancer workforce shortages, where traveling oncologists commute across clinical settings to extend their services. Despite its known benefits specifically for rural patients, oncology outreach reallocates physician resources to satellite clinics and may negatively impact the coordination of cancer care.

Methods: In this retrospective study, we identified patients with incident breast, colorectal, and lung cancers from 2016-2019 nationwide Medicare claims and linked them to oncologists using Part B.

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Objective: The objective of this trial was to determine the feasibility, acceptability, and preliminary effectiveness of sharing audio recordings of primary care visits with older adults with multimorbidity.

Methods: We used a two-arm, randomized, controlled, feasibility trial with 3-month follow-up. Patients aged ≥ 65 years-with diabetes and hypertension-were recruited from academic primary care settings in New Hampshire, Tennessee, and Texas.

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Objective: Physician turnover rates are rising in the United States. The cancer workforce, which relies heavily on clinical teamwork and care coordination, may be more greatly impacted by turnover. In this study, we aimed to characterize oncologists who move to identify targets for recruitment and retention efforts.

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Background: In medical education, particularly in anatomy and dermatology, generative artificial intelligence (AI) can be used to create customized illustrations. However, the underrepresentation of darker skin tones in medical textbooks and elsewhere, which serve as training data for AI, poses a significant challenge in ensuring diverse and inclusive educational materials.

Objective: This study aims to evaluate the extent of skin tone diversity in AI-generated medical images and to test whether the representation of skin tones can be improved by modifying AI prompts to better reflect the demographic makeup of the US population.

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Small calcium-binding proteins such as parvalbumins (PVs) are major seafood and fish allergens. However, the impact of structural changes on their capacity to bind IgE has not been studied in detail. Therefore, fish and reptilian PVs, as well as human α-PV, were selected for biochemical, structural, and IgE binding studies.

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Importance: Leaders of healthcare organizations play a key role in developing, prioritizing, and implementing plans to adopt new evidence-based practices. This study examined whether a letter with peer comparison data and social norms messaging impacted healthcare leaders' decision to access a website with resources to support evidence-based practice adoption.

Methods: Pragmatic, parallel-group, randomized controlled trial completed from December 2019 -June 2020.

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Article Synopsis
  • The study analyzed how travel burden for surgical cancer care is affected by rural living, geographic choices, cancer type, and patient mortality outcomes using Medicare data from 2016-2018.
  • It found that a significant percentage of cancer patients, particularly those in rural areas, chose to bypass their nearest surgical facility, leading to better survival outcomes post-surgery.
  • The research highlights that understanding why rural patients bypass facilities could help improve cancer treatment results and address disparities in cancer care access.
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Article Synopsis
  • Social network analysis has become a key tool in understanding collaborations among physicians, especially in relation to prescribing practices for older patients in Ohio.
  • The concept of homophily suggests that similar individuals (like doctors with similar prescribing habits) are more likely to connect, which can influence interventions aimed at reducing risky-prescribing behaviors.
  • By analyzing Medicare data and using advanced network modeling, the study aims to identify patterns of risky-prescribing among physicians, which could inform targeted group interventions to improve patient safety.
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Importance: Limited availability of inpatient pediatric services in rural regions has raised concerns about access, safety, and quality of hospital-based care for children. This may be particularly important for children with medical complexity (CMC).

Objectives: To describe differences in the availability of pediatric services at acute care hospitals where rural- and urban-residing CMC presented for hospitalization; identify rural-urban disparities in health care quality and in-hospital mortality; and determine whether the availability of pediatric services at index hospitals or the experience of interfacility transfer modified rural-urban differences in outcomes.

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Introduction: Improved access to rehabilitation is highlighted as a key pathway to achieving the World Health Organisation's (WHO) goal of ensuring healthy lives and promoting well-being for all (Sustainable Development Goal 3). This article is the second in a two-part series outlining the findings from the Rehabilitation Choices study, which aimed to identify how health professionals and consumers in Australia are informed to make decisions about rehabilitation, and their experience with barriers and enablers to accessing that rehabilitation. In this study, we present the perspectives of consumers with different health conditions and a range of experiences with rehabilitation services.

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Objective: Direct admission (DA) to hospital can reduce emergency department (ED) utilization by bypassing the ED during the admission process. We implemented a DA program across 3 health systems and compared timeliness of care, family experience of care, and post-admission clinical deterioration among children admitted via DA versus the ED after their clinic was randomized to begin the DA program.

Methods: Using a stepped-wedge design, 69 primary and urgent care clinics were randomized to 1 of 4 time points to begin a voluntary DA program, February 1, 2020 to April 30, 2023.

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Importance: Cancer treatment delay is a recognized marker of worse outcomes. Timely treatment may be associated with physician patient-sharing network characteristics, yet this remains understudied.

Objective: To examine the associations of surgeon and care team patient-sharing network measures with breast cancer treatment delay.

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Importance: Federally qualified health centers (FQHCs) provide care to 30 million patients in the US and have shown better outcomes and processes than other practice types. Little is known about how the COVID-19 pandemic contributed to FQHC capabilities compared with other practices.

Objective: To compare postpandemic operational characteristics and capabilities of FQHCs with non-FQHC safety net practices and non-FQHC, non-safety net practices.

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Article Synopsis
  • * A study using Medicare claims analyzed the rate of ADRD diagnoses in older adults and found that the diagnosis rate varied significantly by hospital referral regions, with lower rates in certain demographic groups such as Black and Hispanic individuals, and those aged 66-74.
  • * The findings suggest that where individuals live significantly affects their chances of receiving an ADRD diagnosis, highlighting the need for targeted efforts in areas with low diagnosis intensity to improve case identification.
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Background And Objectives: Children with medical complexity (CMC) may be at a high risk of neurodevelopmental and mental health conditions given disease comorbidities and lived experiences. Little is known about the prevalence of these conditions at a population level. In this study, we estimated the prevalence of neurodevelopmental and mental health diagnoses in CMC relative to children without medical complexity and measured associations between these diagnoses in CMC and subsequent health care utilization and in-hospital mortality.

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Risky-prescribing is the excessive or inappropriate prescription of drugs that singly or in combination pose significant risks of adverse health outcomes. In the United States, prescribing of opioids and other "risky" drugs is a national public health concern. We use a novel data framework-a directed network connecting physicians who encounter the same patients in a sequence of visits-to investigate if risky-prescribing diffuses across physicians through a process of peer-influence.

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Food choices are closely linked to culture, social relationships, and health. Because many adults spend up to half their time at work, the workplace provides a venue for changing population health-related behaviors and norms. It is unknown whether the effects of a workplace intervention to improve health behaviors might spread beyond participating employees due to social influence.

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Although emergency department (ED) and hospital overcrowding were reported during the later parts of the COVID-19 pandemic, the true extent and potential causes of this overcrowding remain unclear. Using data on the traditional fee-for-service Medicare population, we examined patterns in ED and hospital use during the period 2019-22. We evaluated trends in ED visits, rates of admission from the ED, and thirty-day mortality, as well as measures suggestive of hospital capacity, including hospital Medicare census, length-of-stay, and discharge destination.

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Antibodies are widely used in medicinal and scientific research due to their ability to bind to a specific antigen. Most often, antibodies are composed of heavy and light chain domains. Under physiological conditions, light chains are produced in excess, as compared to the heavy chain.

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Article Synopsis
  • Researchers have characterized the structures of mite profilins for the first time, specifically from the registered allergen Tyr p 36.0101 and Der p profilin, which are unique to arachnids.
  • The study compares the thermal stability of mite and plant profilins, suggesting that more cysteine residues in mite profilins contribute to their greater stability.
  • Despite structural similarities, mite profilins have low sequence identity with plant and human profilins, indicating minimal cross-reactivity with plant profilins, although they retain conserved sites for poly(l-proline) and actin binding.
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Objectives: The clinic visit is a critical point of contact for family caregivers. However, only 37% of family caregivers are able to accompany patients to visits. When they cannot attend, caregivers receive visit information to assist with their caregiving.

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