Publications by authors named "O'Hara N"

Background: Fixation of distal femoral fractures remains a challenge, and nonunions are common with standard constructs. Far cortical locking (FCL) constructs have been purported to lead to improved fracture-healing as compared with that achieved with traditional locking bridge plates. We sought to test this hypothesis in a comparative effectiveness clinical trial.

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Objective: To determine whether bone transport or Masquelet results in higher rates of major unplanned reoperations for the treatment of segmental tibial bone defects ≥4 cm in length.

Methods: Design: Retrospective cohort.

Setting: Level I trauma center.

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Background: Previous research has estimated that over one-half of patients with orthopaedic trauma experience financial distress after the injury. However, it is unknown what proportion of patients lived under financial distress before the injury and, therefore, the causal effect of the injury on financial distress. This study examined changes in financial distress after the injury and factors associated with new post-injury financial distress.

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Objectives: To identify clinical, demographic, and patient-reported outcomes (PROs) associated with return to work after lower extremity traumatic injury requiring amputation or limb salvage.

Methods: Design: Cross-sectional study.

Setting: Multi-center across 25 countries.

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Statistical interpretation is foundational to evidence-based medicine. Frequentist (P value testing) and Bayesian statistics are two major approaches for hypothesis testing. Studies analyzed with Bayesian methods are increasingly common with a 4-fold increase in the past 10 years.

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Objectives: To develop and validate a prediction model for a deep surgical site infection (SSI) after fixation of a tibial plateau or pilon fracture.

Design: Pooled data from 2 randomized trials (VANCO and OXYGEN).

Setting: Fifty-two US trauma centers.

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Objectives: This study aimed to assess the relationship between postoperative alignment and nonunion in patients with tibial shaft fractures treated with intramedullary nailing.

Methods: Design: Retrospective case-control study.

Setting: Single academic trauma center.

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Objectives: To determine the association between closed suction drainage and postoperative infection in patients with tibial plateau or pilon fractures. Secondarily, this study assessed if intrawound vancomycin powder modified the association of closed surgical drains with infection.

Methods: Design: Secondary analysis of the Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial (VANCO) trial.

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Objectives: To determine the effect of external beam radiation (XRT) on preventing severe heterotopic ossification (HO) after acetabular surgery.

Methods: Design: Randomized controlled trial.

Setting: Two level I academic trauma centers.

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Article Synopsis
  • - The study analyzed the OXYGEN trial, which compared high levels of oxygen (80% FiO2) vs. lower levels (30% FiO2) for preventing infections in patients with specific types of fractures and aimed to see if using an "as-treated" approach changed the results compared to the "intention-to-treat" method.
  • - Conducted at 29 trauma centers, 1,231 patients with tibial plateau, tibial pilon, or calcaneus fractures were randomly assigned to either oxygen treatment; adherence was evaluated using two specific criteria based on the percentage of surgery time at different oxygen levels.
  • - Results showed no significant differences in primary and deep infection rates, but the treatment group had fewer
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Background: We aimed to determine if Area Deprivation Index (ADI) is associated with self-reported metrics socioeconomic status (SES), and to assess the relationship between ADI and preoperative score on common patient reported outcome scores (PROS).

Methods: Patients presenting for outpatient orthopaedic surgery completed Patient-Reported Outcome Metric Information System (PROMIS) and joint-specific PROS. ADI was determined from geocoded home address.

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(), formerly known as (), is an anaerobic, low-virulent bacterium that has been associated with postoperative infections of the shoulder, knee, and cervical spine. Recent studies have highlighted an association between and the development of degenerative disc disease (DDD). The aim of this study is to ascertain whether increases the risk of subsidence following anterior cervical discectomy and fusion (ACDF).

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Article Synopsis
  • This study evaluated modified Radiographic Union Scale for Tibia (mRUST) scores over time in patients with distal femur fractures treated with intramedullary nails, to identify factors influencing healing and possible reoperation.
  • Conducted in ten Level I Trauma Centers, the research included 155 fractures from 152 patients, focusing on mRUST scores at 3, 6, and 12 months post-surgery, with the primary goal of finding predictors for union timing.
  • Results showed that a 3-month mRUST score of ≤8 indicated a higher chance of reoperation, and factors such as tobacco use and open fractures correlated with delayed healing times.
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Background: A recent clinical trial suggested aspirin is a viable alternative to enoxaparin for venous thromboembolism (VTE) prophylaxis in patients after orthopedic trauma. The initial impact of these findings on VTE prophylaxis prescribing is unknown. The study aimed to evaluate stated VTE prophylaxis prescribing patterns among clinicians who treat patients after orthopedic trauma.

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Objectives: To investigate and compare the predictive ability of the Orthopaedic Trauma Association-Open Fracture Classification (OTA-OFC) and the Gustilo-Anderson classification systems for fracture-related infections (FRI) in patients with open tibia fractures.

Design: Retrospective cohort study.

Setting: Academic trauma center.

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Objective: To evaluate risk factors for infection in severe open tibial shaft fractures.

Methods: A secondary analysis of a multicenter prospective study investigated internal versus external fixation of severe open tibia fractures at 20 US Level I trauma centers. Adult patients, aged <65 years, with a Gustilo-Anderson Type IIIB or severe IIIA metaphyseal or diaphyseal tibia fracture were included.

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Background: The purpose of this study was to externally validate a predictive score for fracture-related infections, establishing generalizability for absolute and relative risk of infection in the setting of orthopedic fracture surgery.

Materials And Methods: This was a retrospective, case-control study performed at a level I academic trauma center that included 147 patients with fracture-related infection in the study group and 300 control patients. We analyzed the same 8 independent predictors of fracture-related infection cited by a previous study.

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Article Synopsis
  • The study aimed to understand outcome preferences after musculoskeletal trauma among patients and surgeons, emphasizing patient-centered care.
  • Participants ranked various recovery outcomes, revealing that both groups highly valued full recovery without issues, while death ranked as the least preferred outcome.
  • Notably, surgeons placed greater importance on achieving perfect quality of life scores and shorter facility stays compared to patients, highlighting differing perspectives on treatment outcomes.
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The COVID-19 pandemic and subsequent lockdown measures have changed various aspects of society, including patterns of human-animal interactions. This audit investigates the incidence and severity of dog bites admitted under the plastic surgery department at a major trauma centre before and after COVID-19 lockdowns. We assessed trends in dog bite cases over the course of one year (2018) prior to the COVID-19 lockdown and one year after (2022).

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Introduction: Financial toxicity is highly prevalent in patients after an orthopaedic injury. However, little is known regarding the conditions that promote and protect against this financial distress. Our objective was to understand the factors that cause and protect against financial toxicity after a lower extremity fracture.

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"All or none" approaches to the use of contact precautions for methicillin-resistant (MRSA) both fail to recognize that transmission risk varies. This qualitative study assessed healthcare personnel perspectives regarding the feasibility of a risk-tailored approach to use contact precautions for MRSA more strategically in the acute care setting.

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Article Synopsis
  • - The study aimed to analyze the patterns of venous thromboembolism (VTE) testing in patients with orthopedic trauma and assess if VTE surveillance varied according to different prophylaxis regimens, using data from the ADAPT trial.
  • - Conducted as a prospective randomized trial at a Level I trauma center with 329 adult patients, the research recorded VTE imaging studies up to 90 days post-injury and compared testing rates across treatment groups.
  • - Results showed that about 20.4% of patients underwent VTE testing, with no significant differences based on prophylaxis type; however, factors like race, injury severity, and socioeconomic status influenced the likelihood of receiving VTE imaging.
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Objectives: To quantify how patients with lateral compression type 1 (LC1) pelvis fracture value attributes of operative versus nonoperative treatment.

Design: Discrete choice experiment.

Setting: Three US Level 1 trauma centers.

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