Continued professional development (CPD) provision for nurses: A qualitative exploration.

Background: For approximately 1.5 million healthcare practitioners working and registered within the United Kingdom there exists a mandatory requirement to undertake Continued Professional Development. Internationally, healthcare Continued Professional Development is fundamental for frontline staff to practice safely, effectively and maintain up to date skills combined with knowledge.

In praise of postgraduate career clinics: Translating health professionals' willingness to engagement.

Aim: To capture and retain healthcare staff in postgraduate courses relevant to individual career aspirations, service requirements and continuous practice development (CPD) within an English UK university.

Design: Two virtual career clinics for postgraduate practitioners to engage in CPD offers within the university. An online post-enrolment online survey to explore their experiences of engagement with the university.

Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection.

Respiratory viral infections are one of the major causes of illness and death worldwide. Symptoms associated with respiratory infections can range from mild to severe, and there is limited understanding of why there is large variation in severity. Environmental exposures are a potential causative factor.

Confirming Eight-Factor Structure of the Substance Use Motives Measure in a Sample of US College Students.

The 2020 National Survey on Drug Use indicates nearly three quarters of individuals ages 18-25 have used substances in the past year. Research suggests individuals who use substances to cope with negative mood states are typically more substance-involved, report more psychological distress, and have a more extensive treatment history. Additionally, the high rate of polysubstance use among substance using adults in the U.

Psychometric Properties of the MMPI-3 in a Sample of Black and White American Undergraduate Students: Examining Group Differences and Convergent/Discriminant Validity with the ASEBA Adult Self-Report.

The current study examined MMPI-3 internal and external psychometric properties with a focus on the impact of racialized group membership (Black and White Americans). The second aim was to examine convergent/discriminant MMPI-3 scale associations with a different broadband, hierarchical self-report assessment tool [Adult Self-Report (ASR)]. Consistent with findings on prior MMPI iterations, we expected to observe no clinically meaningful mean differences on MMPI-3 scale T-scores.

Three-Dimensionally Printed Simulated Tracheas to Improve Cricothyrotomy Skills Among Anesthesia Providers.

Cricothyrotomy proficiency is imperative for anesthesia providers; however, opportunities to perform this skill are infrequent making skill maintenance essential. Increased accessibility of three-dimensional (3D) printing allows for production of low-cost simulation models. The models used for simulation-based teaching and deliberate practice facilitate skill development and refinement.

Airborne Lidar Measurements of XCO in Synoptically Active Environment and Associated Comparisons With Numerical Simulations.

Frontal boundaries have been shown to cause large changes in CO mole-fractions, but clouds and the complex vertical structure of fronts make these gradients difficult to observe. It remains unclear how the column average CO dry air mole-fraction (XCO) changes spatially across fronts, and how well airborne lidar observations, data assimilation systems, and numerical models without assimilation capture XCO frontal contrasts (ΔXCO i.e.

Viscosity Reduction and Stability Enhancement of Monoclonal Antibody Formulations Using Derivatives of Amino Acids.

Monoclonal antibodies are complex molecules that often require high concentration formulations to meet clinical requirement and bulk drug substance storage. Stability is a common concern in both high and low concentration formulations, however, high concentration formulations are further complicated by an increase in viscosity, leading to manufacturing and administration challenges. To manage stability and viscosity, drug developers typically use salt, amino acids, sugars, polyols, and surfactant.

Alcohol Use and Internalizing Symptoms Among High School students: Does Parental Permission Matter?

This study sought to examine percentages of youth who use alcohol with and/or without parental permission and associations with symptoms of depression and anxiety. At least one in four youth indicated use with parental permission, with approximately 12.7% of youth indicating that they use alcohol both with and without parental permission.

The systems medicine of cannabinoids in pediatrics: the case for more pediatric studies.

Introduction: The legal and illicit use of cannabinoid-containing products is accelerating worldwide and is accompanied by increasing abuse problems. Due to legal issues, the USA will be entering a period of rapidly expanding recreational use of cannabinoids without the benefit of needed basic or clinical research. Most clinical cannabinoid research is focused on adults.

Regional impacts of COVID-19 on carbon dioxide detected worldwide from space.

Activity reductions in early 2020 due to the coronavirus disease 2019 pandemic led to unprecedented decreases in carbon dioxide (CO) emissions. Despite their record size, the resulting atmospheric signals are smaller than and obscured by climate variability in atmospheric transport and biospheric fluxes, notably that related to the 2019–2020 Indian Ocean Dipole. Monitoring CO anomalies and distinguishing human and climatic causes thus remain a new frontier in Earth system science.

Exposure to a mixture of 23 chemicals associated with unconventional oil and gas operations alters immune response to challenge in adult mice.

The prevalence of unconventional oil and gas (UOG) operations raises concerns regarding the potential for adverse health outcomes following exposure to water tainted by mixtures of UOG associated chemicals. The potential effects that exposure to complex chemical mixtures has on the immune system have yet to be fully evaluated. In this study, effects on the immune system of adult mice exposed to a mixture of 23 chemicals that have been associated with water near active UOG operations were investigated.

Atmospheric Carbon and Transport - America (ACT-America) Data Sets: Description, Management, and Delivery.

The ACT-America project is a NASA Earth Venture Suborbital-2 mission designed to study the transport and fluxes of greenhouse gases. The open and freely available ACT-America data sets provide airborne in situ measurements of atmospheric carbon dioxide, methane, trace gases, aerosols, clouds, and meteorological properties, airborne remote sensing measurements of aerosol backscatter, atmospheric boundary layer height and columnar content of atmospheric carbon dioxide, tower-based measurements, and modeled atmospheric mole fractions and regional carbon fluxes of greenhouse gases over the Central and Eastern United States. We conducted 121 research flights during five campaigns in four seasons during 2016-2019 over three regions of the US (Mid-Atlantic, Midwest and South) using two NASA research aircraft (B-200 and C-130).

Publisher Correction: Large Chinese land carbon sink estimated from atmospheric carbon dioxide data.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Local Anomalies in the Column-Averaged Dry Air Mole Fractions of Carbon Dioxide Across the Globe During the First Months of the Coronavirus Recession.

We use a global transport model and satellite retrievals of the carbon dioxide (CO) column average to explore the impact of CO emissions reductions that occurred during the economic downturn at the start of the Covid-19 pandemic. The changes in the column averages are substantial in a few places of the model global grid, but the induced gradients are most often less than the random errors of the retrievals. The current necessity to restrict the quality-assured column retrievals to almost cloud-free areas appears to be a major obstacle in identifying changes in CO emissions.

Large Chinese land carbon sink estimated from atmospheric carbon dioxide data.

Limiting the rise in global mean temperatures relies on reducing carbon dioxide (CO) emissions and on the removal of CO by land carbon sinks. China is currently the single largest emitter of CO, responsible for approximately 27 per cent (2.67 petagrams of carbon per year) of global fossil fuel emissions in 2017.

Expanding the Solubility Parameter Method MOSCED to Pyridinium-, Quinolinium-, Pyrrolidinium-, Piperidinium-, Bicyclic-, Morpholinium-, Ammonium-, Phosphonium-, and Sulfonium-Based Ionic Liquids.

MOSCED (modified separation of cohesive energy density) is a solubility parameter method that offers an improved treatment of association interactions. Solubility parameter methods are well known for their ability to both make quantitative predictions and offer a qualitative description of the underlying molecular-level driving forces, lending themselves to intuitive solvent selection and design. Currently, MOSCED parameters are available for 130 organic solvents, water, and 33 imidazolium-based room temperature ionic liquids (ILs).

The Ancestral Environment Shapes Antiviral CD8 T cell Responses across Generations.

Recent studies have linked health fates of children to environmental exposures of their great grandparents. However, few studies have considered whether ancestral exposures influence immune function across generations. Here, we report transgenerational inheritance of altered T cell responses resulting from maternal (F0) exposure to the aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Response to Comment on "Contrasting carbon cycle responses of the tropical continents to the 2015-2016 El Niño".

Chevallier showed a column CO ([Formula: see text]) anomaly of ±0.5 parts per million forced by a uniform net biosphere exchange (NBE) anomaly of 2.5 gigatonnes of carbon over the tropical continents within a year, so he claimed that the inferred NBE uncertainties should be larger than presented in Liu We show that a much concentrated NBE anomaly led to much larger [Formula: see text] perturbations.

Implementation and evaluation of Stanford Health Care store-and-forward teledermatology consultation workflow built within an existing electronic health record system.

Introduction: Teledermatology services that function separately from patients’ primary electronic health record (EHR) can lead to fragmented care, poor provider communication, privacy concerns and billing challenges. This study addresses these challenges by developing PhotoCareMD, a store-and-forward (SAF) teledermatology consultation workflow built entirely within an existing Epic-based EHR.

Methods: Thirty-six primary care physicians (PCPs) from eight outpatient clinics submitted 215 electronic consults (eConsults) for 211 patients to a Stanford Health Care dermatologist via PhotoCareMD.

Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.

Chemicals used in unconventional oil and gas (UOG) operations have the potential to cause adverse biological effects, but this has not been thoroughly evaluated. A notable knowledge gap is their impact on development and function of the immune system. Herein, we report an investigation of whether developmental exposure to a mixture of chemicals associated with UOG operations affects the development and function of the immune system.

The Multi-Sensor Advanced Climatology of Liquid Water Path (MAC-LWP).

The Multi-Sensor Advanced Climatology of Liquid Water Path (MAC-LWP), an updated and enhanced version of the University of Wisconsin (UWisc) cloud liquid water path (CLWP) climatology, currently provides 29 years (1988 - 2016) of monthly gridded (1°) oceanic CLWP information constructed using Remote Sensing Systems (RSS) inter-calibrated 0.25°-resolution retrievals. Satellite sources include SSM/I, TMI, AMSR-E, WindSat, SSMIS, AMSR-2 and GMI.

Spaceborne detection of localized carbon dioxide sources.

Spaceborne measurements by NASA's Orbiting Carbon Observatory-2 (OCO-2) at the kilometer scale reveal distinct structures of atmospheric carbon dioxide (CO) caused by known anthropogenic and natural point sources. OCO-2 transects across the Los Angeles megacity (USA) show that anthropogenic CO enhancements peak over the urban core and decrease through suburban areas to rural background values more than ~100 kilometers away, varying seasonally from ~4.4 to 6.