Retrospective evaluation of the clinical course and outcome of zinc toxicosis due to metallic foreign bodies in dogs (2005-2021): 55 cases.

Objective: To describe the overall clinical course of zinc toxicosis in dogs including source, time to source control, incidence of hemolytic anemia, acute liver injury (ALI), acute kidney injury (AKI), and pancreatitis.

Design: Retrospective case series from 2005 to 2021.

Setting: Six university veterinary teaching hospitals.

Retrospective analysis of immunosuppressive and anti-thrombotic protocols in nonassociative immune mediated hemolytic anemia in dogs.

Background: Evidence supporting the effectiveness of therapeutic protocols for nonassociative immune-mediated hemolytic anemia (na-IMHA) is weak.

Hypothesis/objectives: Investigate the efficacy of various drugs in na-IMHA.

Animals: Two hundred forty-two dogs.

Peripheral biomarkers of oxidative stress in dogs with acute pancreatitis.

Background: Oxidative stress is considered a pathomechanism of acute pancreatitis (AP), but no studies have extensively characterized oxidant status in dogs with naturally-occurring AP.

Hypothesis Or Objectives: Evaluate measures of oxidant status in dogs with AP and explore whether these measures correlate with AP severity.

Animals: Fifteen dogs with AP and 9 control dogs.

Gastric or duodenal perforation and secondary septic peritonitis following therapeutic nonsteroidal anti-inflammatory drug administration.

Objective: To report which nonsteroidal anti-inflammatory drugs (NSAIDs) were associated with gastric or duodenal perforation (GDP) in dogs presented to a university teaching hospital and to report the frequency of prescription of NSAIDs by the corresponding referring veterinary community during the same time period.

Design: Retrospective cohort study of dogs from January 2007 to March 2020.

Setting: Single university teaching hospital.

Evaluation of resuscitative endovascular balloon occlusion of the aorta catheter placement and comparison to resuscitative thoracotomy with aortic clamping in cadaver dogs.

Objective: To describe placement of an aortic occlusion catheter in aortic zone 1 (Z1) and aortic zone 3 (Z3) in dogs and to compare time to placement in these zones with and without external chest compressions (ECC). Additional evaluations of time to placement in Z1 with time for resuscitative thoracotomy with aortic clamping (RT-AC) were performed.

Design: Prospective ex vivo study.

Evaluation of Veterinary Medical Student Retention of Pre-clinical Concepts with Various Experiential Learning Methods.

Many veterinary medical colleges have undergone curricular changes that have moved away from traditional lecture-based teaching in favor of evidence-based, experiential methods of instruction. Such a curricular reinvention occurred in 2018 at Michigan State University's College of Veterinary Medicine, with individual courses using numerous instructional and learning methods. In the present study, three courses were assessed, two of which used a method of experiential learning, and the other utilizing a traditional lecture approach.

Retrospective evaluation of the prognostic utility of quick sequential organ failure assessment scores in dogs with surgically treated sepsis (2011-2018): 204 cases.

Objective: To assess the prognostic utility of admission quick Sequential Organ Failure Assessment (qSOFA) scores for in-hospital mortality in a population of dogs with surgically treated sepsis.

Design: Retrospective cohort study of dogs from January 2011 to January 2018.

Setting: University teaching hospital.

Retrospective evaluation of feline dystocia: clinicopathologic findings and neonatal outcomes in 35 cases (2009-2020).

Objectives: The aim of this study was to describe the characteristics of cases of feline dystocia presenting to a university emergency service.

Methods: The medical records of queens presenting for dystocia between January 2009 and September 2020 were reviewed. Data collected included queen signalment, presenting complaints, treatments, and maternal and neonatal outcomes.

Retrospective evaluation of the effects and outcome of bromethalin ingestion: 192 Dogs (2010-2016).

Objective: To evaluate the frequency of clinical signs, dose ingested, and outcome in a large group of dogs with bromethalin ingestion.

Design: Retrospective cohort study of dogs from 2010 to 2016.

Setting: Three university teaching hospitals and 1 private practice.

Iatrogenic Urethral Trauma During Routine Prescrotal Orchiectomy in a Dog.

A 6-month-old neutered male redbone coonhound was presented for a 2-day history of progressive subcutaneous swelling that began immediately following a routine prescrotal orchiectomy. Severe, fluctuant swelling and bruising of the ventral thorax, abdomen, scrotum, and right pelvic limb was apparent on examination. No evidence of an underlying coagulopathy was detected.

Mesenteric Lymphadenitis Causing Septic Peritonitis in Two Dogs.

This report describes two cases of mesenteric lymphadenitis leading to septic peritonitis in two young dogs. The cases were similar in presentation, diagnosis, treatment, and length of hospitalization. Both cases presented with clinical signs of vomiting, abdominal pain, and fever and were treated successfully via surgical debridement, omentalization, and antibiotic therapy.

Retrospective evaluation of intravenous premixed amiodarone use and adverse effects in dogs (17 cases: 2011-2014).

Objective: The goal of this study was to evaluate the number and frequency of adverse effects in a population of clinical canine patients receiving Nexterone.

Animals: Seventeen canine patients receiving Nexterone (five of which were treated during cardiopulmonary arrest).

Methods: An electronic records search for canine patients receiving intravenous Nexterone at the Michigan State University Veterinary Teaching Hospital was performed and retrospectively evaluated for patient demographic information, pre- and post-treatment values for heart rate, blood pressure and rhythm diagnosis, as well as any documented adverse effects (hypotension, anaphylaxis, vomiting, phlebitis, and death).

Salmonella Enteritidis-induced alteration of inflammatory CXCL chemokine messenger-RNA expression and histologic changes in the ceca of infected chicks.

To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight genes: CXCLi1[K60], CXCLi2 [IL-8/CAF], interferon (IFN)-gamma, interleukin (IL)-1beta, IL-6, IL-12alpha, IL-12beta, and gallinacin (Gal)-2 in the ceca of young chicks 1 wk postinoculation with SE. Cecum tissue sections were stained and evaluated for the presence of macrophages, lymphocytes, heterophils, and apoptotic cells following SE infection. With the use of quantitative reverse transcriptase-polymerase chain reaction (RT-PCR), SE infection was associated with a significant (P < 0.