Publications by authors named "Nyarai Desiree Soko"
Article Synopsis
- * The drug's effectiveness is influenced by various genetic factors and its metabolism by specific enzymes, which differ among populations worldwide.
- * There is a notable lack of pharmacogenetic research on tamoxifen in African populations, emphasizing the need for targeted studies to enhance treatment outcomes and reduce side effects for African breast cancer patients.
Pharmacogenomics may improve patient care by guiding drug selection and dosing; however, this requires prior knowledge of the pharmacogenomics of drugs commonly used in a specific setting. The aim of this study was to identify a preliminary set of pharmacogenetic variants important in Southern Africa. We describe comorbidities in 3997 patients from Malawi, South Africa, and Zimbabwe.
View Article and Find Full Text PDFStudies in Caucasian and Asian populations consistently associated interindividual and interethnic variability in rosuvastatin pharmacokinetics to the polymorphisms SLCO1B1 c.521T>C (rs4149056 p. Val174Ala) and ABCG2 c.
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