Publications by authors named "Nuzhat Surve"
Article Synopsis
- Scabies is a highly contagious skin disease affecting over 200 million people globally, especially children in poor and crowded areas, leading to significant health issues.
- The lack of a vaccine and limited treatment options, like topical permethrin and oral ivermectin, often results in treatment failures due to fast-acting parasites and the need for multiple treatments.
- Addressing scabies requires a comprehensive strategy, focusing on better diagnostic tools, new treatments, enhanced surveillance, and raising public awareness to break the cycle of infection.
Group A streptococci can trigger autoimmune responses that lead to acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Some autoantibodies generated in ARF/RHD target antigens in the S2 subfragment region of cardiac myosin. However, little is known about the kinetics of these antibodies during the disease process.
View Article and Find Full Text PDFBackground: Anti-myosin antibodies (AMAs) are often formed in response to myocardial infarction (MI) and have been implicated in maladaptive cardiac remodelling. We aimed to: (1) compare AMA formation in patients with Non-ST-Elevation MI (NSTEMI) and ST-Elevation MI (STEMI); (2) evaluate factors predicting autoantibody formation; and, (3) explore their functional significance.
Methods: Immunoglobulin M (IgM) and Immunoglobulin G (IgG) AMA titres were determined in serum samples collected at admission, 3 and 6 months post MI.