Publications by authors named "Nuwan Madusanka"

Parkinson's disease (PD) is a neurodegenerative disorder affecting motor and non-motor functions, including speech. This study evaluates the effectiveness of the audio spectrogram transformer (AST) model in detecting PD through vocal biomarkers, hypothesizing that its self-attention mechanism would better capture PD related speech impairments compared to traditional deep learning approaches. Speech recordings from 150 participants (100 from PC-GITA: 50 PD, 50 healthy controls (HC); 50 from Italian Parkinson's voice and speech (ITA): 28 PD, 22 HC) were analyzed using the AST model and compared against established architectures including VGG16, VGG19, ResNet18, ResNet34, vision transformer, and swin transformer.

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Introduction: This research assesses HRNet and ResNet architectures for their precision in localizing hand acupoints on 2D images, which is integral to automated acupuncture therapy.

Objectives: The primary objective was to advance the accuracy of acupoint detection in traditional Korean medicine through the application of these advanced deep-learning models, aiming to improve treatment efficacy.

Background: Acupoint localization in traditional Korean medicine is crucial for effective treatment, and the study aims to enhance this process using advanced deep-learning models.

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Article Synopsis
  • Researchers have developed a manual-to-powered wheelchair conversion kit that uses a hybrid control system combining electroencephalogram (EEG) and electromyography (EMG), aiming to assist users with diminished muscle strength or paresis.
  • The system achieved impressive accuracy rates (85% overall, 97.3% with LSTM) in detecting user attentiveness and navigation intentions, using a low-cost EEG headset and EMG armband for ease of use.
  • This innovation aims to improve the quality of life for older and disabled individuals by making powered wheelchairs more accessible and user-friendly.
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Speech impairments often emerge as one of the primary indicators of Parkinson's disease (PD), albeit not readily apparent in its early stages. While previous studies focused predominantly on binary PD detection, this research explored the use of deep learning models to automatically classify sustained vowel recordings into healthy controls, mild PD, or severe PD based on motor symptom severity scores. Popular convolutional neural network (CNN) architectures, VGG and ResNet, as well as vision transformers, Swin, were fine-tuned on log mel spectrogram image representations of the segmented voice data.

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Accurate classification of cancer images plays a crucial role in diagnosis and treatment planning. Deep learning (DL) models have shown promise in achieving high accuracy, but their performance can be influenced by variations in Hematoxylin and Eosin (H&E) staining techniques. In this study, we investigate the impact of H&E stain normalization on the performance of DL models in cancer image classification.

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Article Synopsis
  • The study focuses on identifying biomarkers to differentiate prostate cancer (PCa) grade groups by analyzing cell nucleus clusters in histopathological sections using computer-based methods.
  • Researchers utilized both traditional (unsupervised) and modern (supervised) AI techniques for cell nuclei segmentation, clustering, and classification, employing algorithms like minimum spanning tree and K-medoids.
  • The findings highlight the potential of cluster features in cancer grading, but indicate that further validation is needed to improve classification accuracy between different grades of PCa.
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Aims: To prevent Alzheimer's disease (AD) from progressing to dementia, early prediction and classification of AD are important and they play a crucial role in medical image analysis.

Background: In this study, we employed a transfer learning technique to classify magnetic resonance (MR) images using a pre-trained convolutional neural network (CNN).

Objective: To address the early diagnosis of AD, we employed a computer-assisted technique, specifically the deep learning (DL) model, to detect AD.

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Background: In this study, we investigated the effect of hippocampal subfield atrophy on the development of Alzheimer's disease (AD) by analyzing baseline magnetic resonance images (MRI) and images collected over a one-year follow-up period. Previous studies have suggested that morphological changes to the hippocampus are involved in both normal ageing and the development of AD. The volume of the hippocampus is an authentic imaging biomarker for AD.

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Background: We propose a classification method for Alzheimer's disease (AD) based on the texture of the hippocampus, which is the organ that is most affected by the onset of AD.

Methods: We obtained magnetic resonance images (MRIs) of Alzheimer's patients from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. This dataset consists of image data for AD, mild cognitive impairment (MCI), and normal controls (NCs), classified according to the cognitive condition.

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Background: In this study, we used a convolutional neural network (CNN) to classify Alzheimer's disease (AD), mild cognitive impairment (MCI), and normal control (NC) subjects based on images of the hippocampus region extracted from magnetic resonance (MR) images of the brain.

Methods: The datasets used in this study were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI). To segment the hippocampal region automatically, the patient brain MR images were matched to the International Consortium for Brain Mapping template (ICBM) using 3D-Slicer software.

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Background: In this study, we investigated the fusion of texture and morphometric features as a possible diagnostic biomarker for Alzheimer's Disease (AD).

Methods: In particular, we classified subjects with Alzheimer's disease, Mild Cognitive Impairment (MCI) and Normal Control (NC) based on texture and morphometric features. Currently, neuropsychiatric categorization provides the ground truth for AD and MCI diagnosis.

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Microscopic biopsy images are coloured in nature because pathologists use the haematoxylin and eosin chemical colour dyes for biopsy examinations. In this study, biopsy images are used for histological grading and the analysis of benign and malignant prostate tissues. The following PCa grades are analysed in the present study: benign, grade 3, grade 4, and grade 5.

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