Publications by authors named "Nurul Ismail"

The gas sweetening process is essential for removing harmful acid gases, such as hydrogen sulfide (HS) and carbon dioxide (CO), from natural gas before delivery to end-users. Consequently, chemical absorption-based acid gas removal units (AGRUs) are widely implemented due to their high efficiency and reliability. The most common solvent used in AGRU is monodiethanolamine (MDEA), often mixed with piperazine (PZ) as an additive to accelerate acid gas capture.

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The integration of compatibilisers with thermoplastics has revolutionised the field of polymer composites, enhancing their mechanical, thermal, and rheological properties. This study investigates the synergistic effects of incorporating SEBS-g-MAH on the mechanical, thermal, and rheological properties of polycarbonate/acrylonitrile-butadiene-styrene/graphene oxide (PC/ABS/GO) (PAGO) and the properties of polycarbonate/acrylonitrile-butadiene-styrene/graphene oxide (PC/ABS/rGO) (PArGO) composites through the melt blending method. The synergistic effects on thermal stability and processability were analysed by using thermogravimetry (TGA), melt flow index (MFI), and Fourier-transform infrared spectroscopy (FTIR).

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Background: Mental health problems among junior doctors in Malaysia pose a significant concern, as they not only adversely affect their overall well-being but also impact the quality of health services they provide. Therefore, it is important to implement interventions aimed at preserving their mental health. This study aimed to evaluate the effectiveness of the Sanubari Optimal Health Program (OHP) intervention in enhancing the mental well-being of junior doctors in Malaysia.

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Herbal treatments have been utilized for millennia to cure a variety of ailments. There are over 20, 000 herbal remedies available to treat cancer and other disease in humans. In Ayurveda, traditional plants having revitalizing and nourishing characteristics are known as "Rasayanas.

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The Malayan tapir () is listed as Endangered on the IUCN Red List due to multiple threats such as habitat loss and human disturbance that have led to its population decline. This decline increases the risk of inbreeding, which could result in the reduction of genome-wide genetic variation and negatively affect the gene responsible for immune response , MHC gene. Class I and II MHC genes are responsible for encoding MHC molecules in the cells that recognise pathogenic peptides and present them to T-Cells on the cell surface for adaptive immune response.

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One would expect maternal immune cells to attack the invading trophoblast as the placenta is semi-allogenic. However, they appear to cooperate with the trophoblast in disrupting the arterial wall which has been determined in several studies. uNK cells are a particular type of immune cell that appears to play a role in pregnancy.

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Lead (Pb) exposure can be harmful to public health, especially through drinking water. One of the promising treatment methods for lead contaminated water is the adsorption-filtration method. To ensure the cost-effectiveness of the process, naturally derived adsorbent shall be utilised.

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In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSVD). Although NLRP3 inflammasome-interleukin (IL)-1β has been implicated in the pathophysiology of coronary artery disease, its roles in cerebral arteriothrombotic micro-circulation disease such as CSVD remains unexplored. Here, we elaborate on the current manifestations of CSVD and its' complex pathogenesis and relate the array of activators and aberrant activation involving NLRP3 inflammasome with this condition.

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Since its revelation over 14 centuries ago, the Holy Quran is considered as scriptural divine words of Islam, and it is believed to promote psycho-spiritual therapeutic benefits to its reciter and/or listener. In this context, the listening of rhythmic Quranic verses among Muslims is often viewed as a form of unconventional melodic vocals, with accompanied anecdotal claims of the 'Quranic chills' pleasing effect. However, compared to music, rhythm, and meditation therapy, information on the neural basis of the anecdotal healing effects of the Quran remain largely unexplored.

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Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as (), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria.

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KIR2DL4 is an interesting receptor expressed on the peripheral blood natural killer (pbNK) cell as it can be either activating or inhibitory depending on the amino acid residues in the domain. This model uses mathematical modelling to investigate the downstream effects of natural killer cells' activation (KIR2DL4) receptor after stimulation by key ligand (HLA-G) on pbNK cells. Development of this large pathway is based on a comprehensive qualitative description of pbNKs' intracellular signalling pathways leading to chemokine and cytotoxin secretion, obtained from the KEGG database (https://www.

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The role of RhoG in T cell development is redundant with other Racs subfamily members, and this redundancy may be attributed to redundant signal transduction pathways. However, the absence of RhoG increases TCR signalling and proliferation, implying that RhoG activity is critical during late T cell activation following antigen-receptor interaction. Moreover, RhoG is required to halt signal transduction and prevent hyper-activated T cells.

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Despite having high economical value and declining wild population, the aquaculture of the Malaysian mahseer () is still way behind. Crucial information such as on its sexual dimorphism is scarce thus making its broodstock management in captivity challenging. The first step in studying fish sexual dimorphism is by observing and identifying the morphological differences between each sex.

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Cyanobacteria are promising chassis strains for the photosynthetic production of platform and specialty chemicals from carbon dioxide. Their efficient light harvesting and metabolic flexibility abilities have allowed a wide range of biomolecules, such as the bioplastic polylactate precursor D-lactate, to be produced, though usually at relatively low yields. In order to increase photosynthetic electron flow towards the production of D-lactate, we have generated several strains of the marine cyanobacterium sp.

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Background: The influence of past familial experiences of receiving cardiopulmonary resuscitation (CPR) and medical help in various cardiac arrest and nonfatal cardiac events toward willingness to "pay it forward" by helping the next cardiac arrest victim was explored.

Methods: Using a validated questionnaire, 6248 participants were asked to rate their willingness to perform bystander chest compression with mouth-to-mouth ventilation and chest compression-only CPR. Their past familial experiences of receiving cardiopulmonary resuscitation (CPR) and medical help in various cardiac arrest and nonfatal cardiac events were also recorded.

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The vanadium (V) and nitrogen (N) dopants on TiO₂ demonstrated superior photocatalytic performance for the degradation of methylene blue (MB) dye under visible light. The vanadium, V, N-co-doped TiO₂ was synthesized by a modified sol-gel method. It revealed that V and N codoping had a significant effect on the band gap () of TiO₂, where the pristine TiO₂ possessed a wide band gap (3.

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Asthma is a chronic inflammatory disorder in the airways that involves the activation of cells and mediators. (Cooke) Ryvardan or Tiger Milk mushroom is a medicinal mushroom that is traditionally used to treat inflammatory diseases including asthma. In this study, the protective effects of intranasal administration of extract (LRE) in ovalbumin (OVA)-induced airway inflammation mouse model were investigated.

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Background: Orthosiphon aristatus (Blume) Miq. is a medicinal herb which is traditionally used for the treatment of diabetes and kidney diseases in South East Asia. Previous studies reported higher concentration of antioxidative phytochemicals, especially rosmarinic acid (ester of caffeic acid) and other caffeic acid derivatives in this plant extract than the other herbs such as rosemary and sage which are usually used as raw materials to produce rosmarinic acid supplement in the market.

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Poor sperm motility is a common cause of male infertility for which there are no empirical therapies. Sperm motility is powered by adenosine triphosphate but the relative importance of lactate fermentation and Oxidative Phosphorylation (OxPhos) is debated. To study the relationship between energy metabolism and sperm motility we used dissolution Dynamic Nuclear Polarization (dDNP) for the first time to show the rapid conversion of C-pyruvate to lactate and bicarbonate, indicating active glycolytic and OxPhos metabolism in sperm.

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Kratom (Mitragyna speciosa) is a widely abused herbal drug preparation in Southeast Asia. It is often consumed as a substitute for heroin, but imposing itself unknown harms and addictive burdens. Mitragynine is the major psychostimulant constituent of kratom that has recently been reported to induce morphine-like behavioural and cognitive effects in rodents.

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Dengue infections are currently estimated to be 390 million cases annually. Yet, there is no vaccine or specific therapy available. Envelope glycoprotein E (E protein) of DENV mediates viral attachment and entry into the host cells.

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Kratom (or Ketum) is a psychoactive plant preparation used in Southeast Asia. It is derived from the plant Mitragyna speciosa Korth. Kratom as well as its main alkaloid, mitragynine, currently spreads around the world.

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Plant resistance to pathogens is commonly associated with a hypersensitive response (HR), but the degree to which the HR is responsible for incompatibility is subject to debate. Resistance to aphids is likely to share features with resistance to pathogens but is less well understood. Here, we report effective resistance to the pea aphid Acyrthosiphon pisum in Medicago truncatula.

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