Biotransformation of curcumin by K1-18 isolated from mangrove soil.

Biotransformation is recognised as a green chemistry tool to synthesise diverse natural product analogues for valorisation of their chemistry and bioactivities. It offers significant benefits compared to chemical synthesis, given its cost-effectiveness and greater selectivity. In this work, a curcumin analogue, namely gingerenone A, was yielded from the biotransformation process catalysed by .

Enantioselective dihydroxylation of xanthorrhizol from biotransformation using .

Biotransformation is acknowledged as one of the green chemistry methods to synthesis various analogues for further valorization of natural product compounds chemistry and bioactivities. It has huge advantage over chemical synthesis due to its cost-efficiency and higher selectivity. In this work, a xanthorrhizol derivatives, namely (7 ,10)-10,11-dihydro-10,11-dihydroxyxanthorrhizol was produced in 60% yield from the biotransformation process utilizing .

Optimisation of Vitamin B12 Extraction from Green Edible Seaweed () by Applying the Central Composite Design.

Vitamin B12, only found naturally in animal-based foods, is essential for brain functions and various chemical reactions in the human body. Insufficient vitamin B12 leads to vitamin B12 deficiency, common among strict vegetarians due to their limited intake of animal-based foods. Nevertheless, extensive studies have demonstrated that macroalgae, specifically the species, are rich in vitamin B12 and could be further exploited in future dietary applications.

New sesquiterpene dilactone and -carboline alkaloid and the -glucosidase inhibitory activity of selected phytochemicals from (L.) Kosterm.

One new sesquiterpene dilactone, coccinine () and one new -carboline alkaloid, daibucarboline F () together with 10 known compounds; linderane (), linderalactone (), pseudoneolinderane (), linderanlide C (), linderanine A (), epicatechin (), (-)-taxifolin (), astilbin (), L-quercitrin () and afzelin () were isolated from the stems and leaves of (L.) Kosterm (Lauraceae). The structures of ( and ) were established by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in literature.

Biotransformation of sesquiterpenoids: a recent insight.

Sesquiterpenoids have been identified as natural compounds showing remarkable biological activities found in medicinal plants. There is great interest in developing methods to obtain sesquiterpenoids derivatives and biotransformation is one of the alternative methods for structural modification of complex sesquiterpenes structures. Biotransformation is a great drug design tool offering high selectivity and green method.

α-Glucosidase and 15-Lipoxygenase Inhibitory Activities of Phytochemicals from Calophyllum symingtonianum.

A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a positive result against 15-lipoxygenase inhibition.