Publications by authors named "Nurmawarnis Mat Hussin"
RANK, RANKL, and OPG in recurrent solid/multicystic ameloblastoma: their distribution patterns and biologic significance.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2015
Article Synopsis
- The study aims to investigate the expression patterns of bone resorption regulators (RANK, RANKL, and OPG) in recurrent ameloblastoma (RA) to understand their influence on tumor behavior.
- Fifteen RA cases were analyzed using immunohistochemistry, revealing a complex distribution of these proteins, with strong RANK expression in the tumor epithelium, low RANKL levels, and higher OPG presence in the neoplastic epithelium.
- The findings indicate a unique RANK(+)/RANKL(low)/OPG(+) profile in RA, implying altered bone metabolism with reduced resorptive activity in these tumors.