Lactobacillus acidophilus regulates abnormal serotonin availability in experimental ulcerative colitis.

Objectives: Probiotics are known to play a beneficial role in curing irritable bowel syndrome such as ulcerative colitis. Commensal Lactobacillus species are thought to play a protective role against ulcerative colitis, as they restore homeostasis in intestinal disorders. Abnormal serotonin availability has been described in ulcerative colitis, but the underlying mechanism is still unclear.

Probiotics in Experimental Ulcerative Colitis: Mast Cell Density and Neuronal Hypertrophy.

Background: Probiotics such as Lactobacillus and Bifidobacterium are among the supportive treatment methods to achieve effective results in ulcerative colitis. This study was established to investigate the effect of probiotics in experimental ulcerative colitis and to detect changes in mast cell and neuronal structures in this treatment method.

Methods: A total of 48 adult male rats were used to study the effects of probiotics on ulcerative colitis.