Publications by authors named "Nuria Serre-Delcor"

Background: The growing number of vulnerable migrants and refugees (VMRs) in the European Union presents challenges to healthcare systems, emphasizing the need for enhanced intercultural competence training for healthcare professionals. Educational escape rooms, using gamification-based principles, may offer an innovative solution to improve these competencies.

Objective: This pilot study evaluates the acceptability and preliminary effectiveness of an educational escape room aimed at improving intercultural competence, self-efficacy, and knowledge among healthcare students and professionals caring for VMRs.

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  • Hypereosinophilic syndrome can affect the heart and is often linked to poor outcomes, but there's limited data on its impact on Latin American migrants with eosinophilia from parasitic infections.
  • A study was conducted with individuals from Latin America, comparing those with eosinophilia and helminth infections to those without, using echocardiography and microbiological tests for diagnosis.
  • Results showed that participants with eosinophilia had significant echocardiographic changes, like increased heart wall thickness and altered heart function, suggesting early signs of heart dysfunction potentially due to eosinophilia-related effects.
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Background: Acute schistosomiasis occurs most often in travelers to endemic regions. The aim of the study is to describe the epidemiological, clinical and parasitological characteristics of patients with schistosomiasis acquired during an international travel.

Methods: Observational retrospective study including all travel-related schistosomiasis cases seen at the International Health Unit Vall d'Hebron-Drassanes (Barcelona, Spain) from 2009 to 2022.

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Introduction: Almost 281 million people were living in a foreign country in 2022, and more than 100 million were displaced because of war conflicts and human right violations. Vaccination coverage of infectious diseases in migrants from some disadvantaged settings could be lower than reception countries populations, consequently seroprevalence studies and better access to vaccination could contribute to reducing these differences.

Methods: A descriptive retrospective cross-sectional study was conducted including migrants, living ≤5 years in the reception country and ≥16 years old, who requested a medical exam between January 1st, 2020 and January 31st, 2021.

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  • High-speed global travel, migration, and climate change have contributed to the rise of imported infections in Spain from 2012 to 2022, necessitating analysis of these trends.
  • The study used data from the +Redivi network, involving 25 health centres, to assess demographics and diagnostic outcomes related to these infections among various groups, including migrants and travelers.
  • Findings revealed stable rates for some infections like malaria, while others such as schistosomiasis and tuberculosis saw increased diagnoses, highlighting significant interactions based on time and participant demographics.
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Migrant patients share the same diseases as natives, but biological or environmental differences may lead to distinct prevalence and manifestations of certain syndromes. Some common conditions in Primary Care stand out, such as fever, diarrhea, anemia, eosinophilia, and chronic cough, where it is important to have a special consideration. Fever may indicate a serious imported illness, and malaria should always be ruled out.

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  • A 12-year retrospective study was conducted on imported strongyloidiasis cases at the International Health Unit in Barcelona, revealing 865 diagnosed cases predominantly among young male migrants, primarily from Latin America.
  • Most patients sought consultation for health screenings or laboratory test alterations, with a significant rise in case numbers observed in recent years.
  • The findings suggest that improved screening strategies can enhance detection and treatment of asymptomatic cases, potentially lowering the risk of complications.
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Background: Treatment with benznidazole for chronic Chagas disease is associated with low cure rates and substantial toxicity. We aimed to compare the parasitological efficacy and safety of 3 different benznidazole regimens in adult patients with chronic Chagas disease.

Methods: The MULTIBENZ trial was an international, randomised, double-blind, phase 2b trial performed in Argentina, Brazil, Colombia, and Spain.

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  • * Among the 261 patients, 63 experienced at least one AE, with those on immunosuppressive treatment showing a higher risk of complications; 226 patients (86.6%) completed their treatment successfully.
  • * Different groups showed varying risks for AEs and treatment success, indicating the need for tailored adherence plans and AE management, especially for immunosuppressed individuals and recent immigrants from high TB incidence countries.
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  • A 17-year-old male from The Gambia, who showed no symptoms, was evaluated during a routine health check after moving to Spain.
  • Laboratory tests revealed the presence of microfilariae, which are larvae of certain parasites.
  • This case highlights the critical need for thorough health screenings and detailed travel histories for migrants to detect potential health issues early on.
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  • Prolonged gastrointestinal symptoms can occur after recovering from traveller's diarrhoea (TD), leading to a condition known as post-infectious irritable bowel syndrome (PI-IBS), which can last for at least 6 months.
  • A study conducted on patients from Barcelona identified that 10.2% of those who suffered from TD went on to develop PI-IBS, with a significant number being linked to parasitic infections, especially Giardia duodenalis.
  • Additionally, factors such as pre-travel counselling were found to decrease the likelihood of developing PI-IBS after returning from trips, particularly to regions like Latin America and the Middle East.
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  • There is currently no unanimous agreement on the best screening methods for schistosomiasis in asymptomatic individuals from non-endemic areas.
  • This study aimed to assess the effectiveness of direct microscopy and ELISA serology for schistosomiasis screening among a high-risk group in Barcelona, evaluating data from 440 individuals primarily from West Africa.
  • The results showed that schistosomiasis was common in this population, with similar effectiveness in detection between serological and microscopic methods, while younger age, eosinophilia, and elevated IgE levels were frequently observed in diagnosed cases.
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Objectives: Strongyloidiasis is a nematode infection caused by Strongyloides stercoralis. Previous studies have addressed the possibility of the parasite to establish a complex relationship with the host that could affect the risk of developing diabetes mellitus or modify its presentation. This study aims to evaluate the potential impact of strongyloidiasis in diabetes mellitus and other metabolic diseases.

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This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed consent form, recording the patient's data in a web-based database system, and performing the rapid test and blood collection on dry paper.

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Background: Unaccompanied and separated children (UASC) are a high-risk group for infectious diseases and information on their vaccination status is scarce. Different approaches are used to screen newly arrived minors in Europe. The aim of this study was to describe the health status and serological protection against different vaccine-preventable diseases among UASC to inform public health decision-making.

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MyHealth European project (2017-2020) was committed to elaborate on models to engage vulnerable migrants and refugees (VMR) in their health through community involvement. Low healthcare access and poor quality of healthcare services for VMR is a common reality in many European countries. The purpose of the present study, as part of MyHealth project, was the development of an agenda for actions and consequent recommendations to tackle the issue.

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  • Benznidazole is the primary treatment for Chagas disease, but over 50% of patients experience adverse effects, with cutaneous reactions being common and causing about 15% to stop treatment.
  • A study was conducted to confirm the link between these skin reactions and the presence of the HLA-B∗35:05 allele, involving 207 Chagas patients primarily from Bolivia.
  • Results showed that nearly half of the participants had cutaneous reactions, with significant predictors for more severe reactions including being female, having eosinophilia, and carrying the HLA-B∗35 allelic group.
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Background: The aim of the study is to describe the epidemiological, clinical, and microbiological characteristics of patients with diarrhoea after their return from a trip to tropical and subtropical areas.

Methods: Retrospective study of patients with travel-related diarrhoea attended International Health referral center. Travel diarrhoea was defined as the presence of three or more liquid stools per day, or liquid stools more often than is normal for the individual, during travel or within two weeks after returning.

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Background: Leishmaniasis is a neglected disease caused by different species of the protozoa Leishmania spp. Cutaneous lesions are the most common clinical manifestation. This disease is prevalent in tropical and subtropical areas, including the Mediterranean basin.

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Background: Chagas disease is a public health problem not only in Latin America, but also in other regions, including Spain, due to migration movements. Conventional serological diagnosis requires an invasive sample (plasma or serum) and a well-equipped laboratory. To circumvent those limitations, blood samples dried on filter paper (DBS) or Rapid Diagnostic Test (RDT) could be a practical alternative to reference protocol for serological screening in epidemiological studies.

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Heightened conflicts and lack of safety due to reasons related to economic, social, ethnic, religious, sexual orientation, political, or nationality matters have increased migratory movements during the last, few decades. Unfortunately, when migrants arrive in new territories, they can face many barriers. For example, in Spain, some migrants have difficulties in accessing health services.

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