Publications by authors named "Nuria R Roque Rosell"
Bioorg Med Chem Lett
January 2014
Article Synopsis
- Foot-and-mouth disease virus (FMDV) is highly contagious and causes severe economic losses in livestock.
- The viral genome is processed into functional proteins mainly by a crucial enzyme called the 3C protease, which is a promising target for developing antiviral drugs.
- Researchers have created irreversible inhibitors by modifying a peptide to improve its interaction with the protease, revealing that a positively charged component is key to enhancing drug effectiveness.
