Publications by authors named "Nuria Piedra-Carrasco"
The progressive increase of infections produced by extensively drug-resistant carbapenemase-producing Klebsiella pneumoniae (XDR-CPKP) represents an important threat to public health. Unfortunately, optimal therapeutic options are scarce. Retrospective studies have recommended combined therapy with more than one antibiotic and, more recently, a double-carbapenem regimen has been reported to be an effective alternative therapy.
View Article and Find Full Text PDFThe increasing resistance to carbapenems is an alarming threat in the fight against multiresistant bacteria. The dissemination properties of antimicrobial resistance genes are supported by their detection in a diverse population of bacteria, including strains isolated from the environment. The objective of this study was to investigate the presence of carbapenemase-producing Enterobacteriaceae (CPE) collected from a river ecosystem in the Barcelona metropolitan area (Spain).
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- The study analyzed 22 E. coli strains from colibacillosis cases and 10 from avian feces to investigate the virulence and antibiotic resistance of avian pathogenic E. coli (APEC) in poultry.
- It found that 91% of APEC isolates had virulence genes linked to disease, and a high genetic diversity was observed among strains, with many being multi-drug resistant.
- The research highlighted the potential public health threat posed by these resistant genes, suggesting that these bacterial strains could spread to humans through the food chain, thus calling for more studies on their epidemiology.
Flies may act as potential vectors for the spread of resistant bacteria to different environments. This study was intended to evaluate the presence of Escherichia coli strains resistant to cephalosporins in flies captured in the areas surrounding five broiler farms. Phenotypic and molecular characterization of the resistant population was performed by different methods: MIC determination, pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and phylotyping.
View Article and Find Full Text PDFWe report a case of typhoid fever in a traveler returning to Spain from Guatemala that was caused by Salmonella enterica serovar Typhi which produced an extended-spectrum β-lactamase (ESBL). This finding demonstrates the presence of ESBL-producing S. enterica ser.
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