Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats.

3,4-Methylenedioxymethamphetamine (MDMA or "ecstasy") is consumed mainly by young population. For this reason, it is especially relevant to take into consideration the effects on the reproductive system. The influence of MDMA on the fertility and reproduction of the male rat was assessed in this study.