Effect of cefazolin and cefuroxime on fracture healing in rats.

Objective: To determine the effect of cefazolin and cefuroxime (the two most commonly used beta lactam antibiotics) at therapeutic doses in fracture healing in an animal model.

Material And Methods: 75 adult male wistar rats (3months old) were selected. They were divided into three groups of 25 animals each (placebo, cefazolin and cefuroxime).