Publications by authors named "Nuria Andres"
Article Synopsis
- Rheumatoid arthritis (RA) is a long-term inflammatory condition where the immune system attacks joints, leading to varying degrees of disease severity and joint damage for most patients.
- Researchers identified suppressor of cytokine signaling 1 (SOCS1) as a key molecule that may help predict disease outcomes, finding that lower mRNA levels of SOCS1 are linked to worse disease activity and response to treatments like methotrexate and rituximab.
- Genetic variations (single nucleotide polymorphisms) in the SOCS1 gene were also discovered that could aid in identifying early RA patients and their potential disease progression, emphasizing the importance of mRNA levels in guiding treatment decisions.
Article Synopsis
- Growth hormone (GH) influences immune responses by altering the behavior of macrophages, key immune cells involved in inflammation.
- In laboratory studies, GH treatment enhances anti-inflammatory gene expression in macrophages and reduces proinflammatory signals, contributing to a more favorable immune response.
- In experiments with mice suffering from colitis, GH overexpression was linked to better inflammation resolution and tissue repair, showcasing GH's potential role in moderating inflammatory conditions.
Sci Total Environ
May 2019
Article Synopsis
- - The Tröllaskagi Peninsula in northern Iceland contains numerous small glaciers that provide valuable records of climate changes in the Holocene era, challenging previous assumptions about the timing of their maximum extents, which were believed to occur predominantly during the Little Ice Age (LIA).
- - New research using Cosmic-Ray Exposure (CRE) dating on moraine sequences has identified several glacial advances before the LIA, specifically around 400 and 700 CE, in addition to earlier LIA advances in the 15th and 17th centuries.
- - Unlike traditional lichenometric dating, which has limitations for dating earlier glacial advances, this study combines various methods including satellite imagery and field work, highlighting a longer regional colonization lag
