Comparison of the effectiveness and side-effects of tolterodine and oxybutynin in children with detrusor instability.

Background: Treatment with anticholinergic agents is the mainstay of therapy for detrusor instability (DI), a chronic and morbid condition characterized by urge urinary incontinence. The aim of this study is to assess the effectiveness and tolerability of tolterodine and oxybutynin in children with DI.

Methods: A total of 60 children with DI were enrolled, 30 (14 male, 16 female, mean age 7.

Surgical necrotizing enterocolitis: are intestinal lesions more severe in infants with low birth weight?

Purpose: This study examines whether the intestinal lesions of necrotizing enterocolitis (NEC) in infants undergoing surgery are more severe in patients with extremely low birth weight (BW).

Methods: Between 1980 and 2000, 128 infants underwent laparotomy for NEC: 90 in the acute phase, and 38 for secondary stenosis. Resections were limited to areas of transparietal bowel necrosis and to secondary stenoses.