Publications by authors named "Nuri Hong"
Investigation of gene-environment interactions in relation to tic severity.
J Neural Transm (Vienna)
November 2021
Article Synopsis
- Tourette syndrome (TS) is influenced by genetic and environmental factors, and this study investigated how specific genetic variants interact with pre- and perinatal adversity to affect tic severity in individuals with TS.
- Researchers examined 98 single-nucleotide polymorphisms (SNPs) from various sources, including previous GWAS studies, to determine their association with tic severity using linear regression models.
- While one SNP (rs7123010) showed a significant link to higher tic severity, the overall findings regarding the gene-environment interactions were not replicated in a second sample, suggesting more research is needed in this area.
The objective of this study was to investigate stability of cognitive development during the first five years of life in relation to heavy metal concentrations in umbilical cord blood in Korean children. This research is part of the Mothers' and Children's Environmental Health (MOCEH) study, a multi-center prospective birth cohort study of pregnant women in Korea who were recruited from 2006 to 2010. We analyzed the complete follow-up data of children who were 5years-old in 2016.
View Article and Find Full Text PDFThe present study assessed the associations of heavy metal concentrations in pregnant women with the concentrations in their children during early childhood. This study is a part of the Mothers' and Children's Environmental Health (MOCEH) study, a Korean multi-center prospective birth cohort study of 1751 pregnant women who were recruited from 2006 to 2010. We completed the follow-up of children who were 5years-old in 2016.
View Article and Find Full Text PDFThe objective of the present study was to investigate the relationship of IQ in children with maternal blood mercury concentration during late pregnancy. The present study is a component of the Mothers and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project in Korea that began in 2006. The study cohort consisted of 553 children whose mothers underwent testing for blood mercury during late pregnancy.
View Article and Find Full Text PDFArticle Synopsis
- This study evaluated the effectiveness of the weight-to-height ratio (WHtR) as a tool for identifying obesity and metabolic syndrome in Korean youth, comparing it to traditional measures like BMI and waist circumference.
- Data from over 3,000 participants aged 10-19 were analyzed to determine optimal WHtR cutoff values, finding that a WHtR of around 0.50 for boys and 0.47-0.48 for girls was effective for assessing obesity.
- Although WHtR showed slightly better predictive power for metabolic syndrome compared to BMI and waist circumference, the differences weren’t statistically significant, with similar sensitivities and specificities for both genders.
Objective: To investigate whether performance IQ in children is associated with maternal blood cadmium concentration in early pregnancy.
Method: The present study is a component of the Mothers' and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project in Korea that began in 2006. The study cohort consisted of 119 children whose mothers underwent testing of blood cadmium during early pregnancy.
Objective: To investigate whether blood lead concentrations are elevated in iron-deficient children, and to examine the association between iron deficiency and/or elevated blood lead concentration and cognitive deficits in children.
Method: The present study is a component of the Mothers' and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project in Korea that began in 2006. The study cohort consisted of 194 children who underwent testing of blood lead and serum C-reactive proteins (CRPs) and ferritin concentrations, and the Korean version of the Wechsler Preschool and Primary Scale of Intelligence, revised edition (WPPSI-R), at 60 months of age.