Effect of Leaf Extract Towards the Sertoli Cells on Alloxan-Induced Mice.

<b>Background and Objective:</b> Prolonged and uncontrolled hyperglycemia in diabetes mellitus can increase the production of reactive oxygen and enhance the risk of male infertility by reducing the number of Sertoli cells. This study aimed to investigate the potential effect of Ethanol Extract of <i>Annona muricata </i>leaf (EEAL) on the amount of Sertoli cells in alloxan-induced mice antioxidant to prevent reducing the number of Sertoli cells. <b>Materials and Methods:</b> The samples used for this study are 30 alloxan-induced Swiss Webster mice divided into a negative control group, a positive control group (glibenclamide 0.

Ethanol Extract of Pomegranate () Peel in Increasing the Expression of Caspase-3 in DSS-Induced Mice.

Background: Colorectal cancer (CRC) is a malignancy derived from the glandular epithelial cells in the colon. Patients with inflammatory bowel disease (IBD) are more likely to develop CRC. Cancer proliferation is characterized by the loss of inhibition of apoptosis, which involves caspase-3 activation.

Increased Estradiol Levels Effect on Leptin Expression in Midluteal Endometrial Tissue of Macaca Nemestrina (Southern Pig-Tailed Macaques).

To measure the effect of serum estradiol (E2) levels on leptin expression in Macaca nemestrina (southern pig-tailed macaque) endometrial tissue. This study used paraffin-embedded midluteal phase endometrial tissue blocks of Macaca nemestrina from previous study. Included subjects were 15 female macaques of reproductive age (8-10 years) with a previous history of producing offspring, which were divided into four groups: groups administered with 30 IU, 50 IU, and 70 IU r-FSH (intervention group), and no r-FSH (control group).

Expression of E-Cadherin in Pig-Tailed Monkey () Endometrium after Controlled Ovarian Hyperstimulation.

An increase of steroid hormones in controlled ovarian hyperstimulation (COH) procedures is reducing the success rate in assisted reproductive technology (ART), and this includes the pregnancy rate and/or implantation rate. Research has found that the decrease in the success rate occurred due to the decreased expression of the protein that is needed to prepare the endometrium so that the embryo could attach. The aim of the study was to analyse the changes in E-chaderin expression due to COH and its relations with increased level of steroid hormones as one of the proteins in the endometrium.

Increased Progesterone on the Day of Administration of hCG in Controlled Ovarian Hyperstimulation Affects the Expression of HOXA10 in Primates' Endometrial Receptivity.

The increase in progesterone (P4) levels on the day of human chorionic gonadotropin (hCG) administration have a negative effect on endometrial receptivity. There are few reports regarding the expression of homeobox A10 (HOXA10) as one of many biomolecular factors of endometrial receptivity. To evaluate the effect of increased P4 concentration on the day of hCG administration on HOXA10, a total of 16 were divided into three dose groups of recombinant-follicle stimulating hormone (rFSH) (30IU, 50IU, and 70IU) and one control group.