Molecular Basic of Pharmacotherapy of Cytokine Imbalance as a Component of Intervertebral Disc Degeneration Treatment.

Intervertebral disc degeneration (IDD) and associated conditions are an important problem in modern medicine. The onset of IDD may be in childhood and adolescence in patients with a genetic predisposition. With age, IDD progresses, leading to spondylosis, spondylarthrosis, herniated disc, spinal canal stenosis.

Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration.

The intervertebral disk degeneration (IDD) and its associated conditions are an important problem in modern medicine. The onset of IDD may be in childhood and adolescence in patients with a genetic predisposition. IDD progresses with age, leading to spondylosis, spondylarthrosis, intervertebral disk herniation, and spinal stenosis.

[The diagnostic and prognostic characteristics of nephroblastoma recurrences in children].

A total of 450 children with nephroblastoma were treated in the children's oncological department of the All-Union Cancer Research Centre, the USSR Academy of Medical Sciences, between 1976 and 1986. Tumour relapses were diagnosed during various terms of postsurgery in 131 (29.1 per cent) of them: true relapses in 58 (44.

[Reproductive function in persons with a history of Hodgkin's disease in childhood].

The paper presented the immediate and long-term therapeutic response in 141 patients (88 males and 53 females) who had suffered from Hodgkin disease at the age between 3 and 15 years and then were followed up from 5 to 25 years. Their physical and sexual development, occupation, family status were considered. In case the pregnancy was not forbidden terms of its successful development were formulated.